E H. Leiter, et.al., Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice., Diabetes, obesity & metabolism, 2007, 9 Suppl 2

http://rdf.ncbi.nlm.nih.gov/pubmed/17919174

E H. Leiter, et.al., Unexpected functional consequences of xenogeneic transgene expression in beta-cells of NOD mice., Diabetes, obesity & metabolism, 2007, 9 Suppl 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins2-cre)6Lt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762760

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Tg(Ins2-cre)6Lt/0
  http://metadb.riken.jp/0002169NODShiLtTgIns2cre6LtTgIns2cre6Lt0TgIns2cre6Lt
• decreased circulating insulin level_Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
  http://metadb.riken.jp/0002727NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara
• decreased pancreatic beta cell number_Tg(Ins1-EGFP/GH1)14Hara/0
  http://metadb.riken.jp/0003339NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara0TgIns1EGFPGH114Hara
• insulitis_Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
  http://metadb.riken.jp/0004031NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara
• insulitis_Tg(Ins2-cre)5Lt/Tg(Ins2-cre)5Lt
  http://metadb.riken.jp/0004031NODShiLtTgIns2cre5LtTgIns2cre5LtTgIns2cre5LtTgIns2cre5Lt
• increased susceptibility to autoimmune diabetes_Tg(Ins1-EGFP/GH1)14Hara/0
  http://metadb.riken.jp/0004803NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara0TgIns1EGFPGH114Hara
他7件を見る
• increased susceptibility to autoimmune diabetes_Tg(Ins2-cre)5Lt/0
  http://metadb.riken.jp/0004803NODShiLtTgIns2cre5LtTgIns2cre5Lt0TgIns2cre5Lt
• abnormal pancreatic beta cell morphology_Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
  http://metadb.riken.jp/0005217NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara
• impaired glucose tolerance_Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
  http://metadb.riken.jp/0005293NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara
• decreased susceptibility to autoimmune disorder_Tg(Ins1-EGFP/GH1)14Hara/Tg(Ins1-EGFP/GH1)14Hara
  http://metadb.riken.jp/0005351NODShiLtJTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114HaraTgIns1EGFPGH114Hara
• decreased susceptibility to autoimmune disorder_Tg(Ins2-cre)5Lt/Tg(Ins2-cre)5Lt
  http://metadb.riken.jp/0005351NODShiLtTgIns2cre5LtTgIns2cre5LtTgIns2cre5LtTgIns2cre5Lt
• preweaning lethality, complete penetrance_Tg(Ins2-cre)3Lt/Tg(Ins2-cre)3Lt
  http://metadb.riken.jp/0011100NODShiLtTgIns2cre3LtTgIns2cre3LtTgIns2cre3LtTgIns2cre3Lt
• preweaning lethality, complete penetrance_Tg(Ins2-cre)6Lt/Tg(Ins2-cre)6Lt
  http://metadb.riken.jp/0011100NODShiLtTgIns2cre6LtTgIns2cre6LtTgIns2cre6LtTgIns2cre6Lt

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ins2-cre)6Lt
  http://metadb.riken.jp/db/mgi_rdf/MGI:3762760