Nadine. Hövelmeyer, et.al., Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD., The Journal of experimental medicine, 2007, 204

http://rdf.ncbi.nlm.nih.gov/pubmed/17923499

Nadine. Hövelmeyer, et.al., Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD., The Journal of experimental medicine, 2007, 204

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cyld<tm1.1Awai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761624
• Cyld<tm1Awai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761621

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased B-1 B cell number_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0004978NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• increased marginal zone B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008181NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased pro-B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008186NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• decreased immature B cell number_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0008215NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• abnormal spleen morphology_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0000689NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal Peyer's patch germinal center morphology_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0002391NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased B cell number_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0005014NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• enlarged Peyer's patches_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0008136NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• enlarged lymph nodes_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0000702NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• increased IgA level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0002495NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0005014NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• enlarged spleen_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0000691NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• enlarged Peyer's patches_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008136NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• decreased IgM level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0001806NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal B cell physiology_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0002459NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• enlarged spleen_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0000691NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn
• decreased immature B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008215NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• decreased B-1 B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0004978NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• decreased IgG3 level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008498NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal spleen marginal zone morphology_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0002362NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal B cell differentiation_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0002144NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• enlarged lymph nodes_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0000702NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased follicular B cell number_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008173NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal B cell morphology_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0004939NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased IgG2b level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008501NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased IgG2a level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008500NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal humoral immune response_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0001800NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal class switch recombination_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0004816NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• increased IgG1 level_Cyld<tm1.1Awai>/Cyld<tm1.1Awai>
  http://metadb.riken.jp/0008499NSCyldtm11AwaiCyldtm11AwaiCyldtm11Awai
• abnormal mature B cell morphology_Cyld<tm1Awai>/Cyld<tm1Awai>,Tg(CD19-cre/ERT2)1Cgn/?
  http://metadb.riken.jp/0008171NSCyldtm1AwaiCyldtm1AwaiTgCD19creERT21CgnCyldtm1AwaiTgCD19creERT21Cgn

class

http://purl.org/net/cito/citesAsAuthority

• Cyld<tm1.1Awai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761624
• Cyld<tm1Awai>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3761621