Arun. Gupta, et.al., The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis., Molecular and cellular biology, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/17967868

Arun. Gupta, et.al., The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis., Molecular and cellular biology, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kat8<tm2Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769376
• Kat8<tm1Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769362

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cellular sensitivity to ionizing radiation_Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>,Kat8<tm1Thl>/Kat8<+>
  http://metadb.riken.jp/0004227I129S1SvGtROSA26Sortm1creERT2ThlGtROSA26SorKat8tm1ThlKat8GtROSA26Sortm1creERT2ThlKat8tm1ThlGtROSA26SorKat8
• decreased cell proliferation_Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>,Kat8<tm1Thl>/Kat8<+>
  http://metadb.riken.jp/0000352I129S1SvGtROSA26Sortm1creERT2ThlGtROSA26SorKat8tm1ThlKat8GtROSA26Sortm1creERT2ThlKat8tm1ThlGtROSA26SorKat8
• abnormal DNA repair_Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>,Kat8<tm1Thl>/Kat8<+>
  http://metadb.riken.jp/0008058I129S1SvGtROSA26Sortm1creERT2ThlGtROSA26SorKat8tm1ThlKat8GtROSA26Sortm1creERT2ThlKat8tm1ThlGtROSA26SorKat8
• embryonic lethality between implantation and somite formation, complete penetrance_Kat8<tm2Thl>/Kat8<tm2Thl>
  http://metadb.riken.jp/0011096I129S1SvKat8tm2ThlKat8tm2ThlKat8tm2Thl
• decreased body weight_Atm<tm1Led>/Atm<tm1Led>,Kat8<tm2Thl>/Kat8<+>
  http://metadb.riken.jp/0001262I129S1Sv129S6SvEvTacAtmtm1LedAtmtm1LedKat8tm2ThlKat8Atmtm1LedKat8Kat8tm2Thl
• premature death_Atm<tm1Led>/Atm<tm1Led>,Kat8<tm2Thl>/Kat8<+>
  http://metadb.riken.jp/0002083I129S1Sv129S6SvEvTacAtmtm1LedAtmtm1LedKat8tm2ThlKat8Atmtm1LedKat8Kat8tm2Thl
• decreased cell proliferation_Gt(ROSA)26Sor<tm1(cre/ERT2)Thl>/Gt(ROSA)26Sor<+>,Kat8<tm1Thl>/Kat8<tm1Thl>
  http://metadb.riken.jp/0000352I129S1SvGtROSA26Sortm1creERT2ThlGtROSA26SorKat8tm1ThlKat8tm1ThlGtROSA26Sortm1creERT2ThlKat8tm1ThlGtROSA26Sor
• premature death_Kat8<tm2Thl>/Kat8<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002083I129S1Sv129S7SvEvBrdKat8tm2ThlKat8Trp53tm1BrdTrp53tm1BrdTrp53tm1BrdKat8Kat8tm2Thl
• premature death_Atm<tm1Led>/Atm<+>,Kat8<tm2Thl>/Kat8<+>
  http://metadb.riken.jp/0002083I129S1Sv129S6SvEvTacAtmtm1LedAtmKat8tm2ThlKat8Kat8tm2ThlKat8Atmtm1LedAtm
• abnormal embryo development_Kat8<tm2Thl>/Kat8<tm2Thl>
  http://metadb.riken.jp/0001672I129S1SvKat8tm2ThlKat8tm2ThlKat8tm2Thl

class

http://purl.org/net/cito/citesAsAuthority

• Kat8<tm2Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769376
• Kat8<tm1Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769362