Joanne. Shi, et.al., Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis., Developmental biology, 2008, 313

http://rdf.ncbi.nlm.nih.gov/pubmed/18022611

Joanne. Shi, et.al., Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis., Developmental biology, 2008, 313

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Mmp16<tm1Khol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771975

class

http://purl.org/net/cito/citesAsAuthority

• Mmp16<tm1Khol>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771975

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• short humerus_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0004351I129P2OlaHsdMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal parietal bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000109I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal long bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0003723I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• small cranium_Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0005352I129S6SvEvTacMmp16tm1KholMmp16tm1KholMmp16tm1Khol
• abnormal neurocranium morphology_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000074I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0000166I129P2OlaHsdMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• abnormal skeleton morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0005508I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal compact bone morphology_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003797I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal cartilage morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0000163I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• palatal shelf hypoplasia_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0009883I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• absent bone trabeculae_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0010870I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• cleft secondary palate_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0009890I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal neurocranium morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0000074I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• postnatal growth retardation_Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0001732I129S6SvEvTacMmp16tm1KholMmp16tm1KholMmp16tm1Khol
• domed cranium_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000440I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• postnatal lethality, complete penetrance_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0011085I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• short humerus_Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0004351I129S6SvEvTacMmp16tm1KholMmp16tm1KholMmp16tm1Khol
• abnormal long bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003723I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• small cranium_Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0005352I129S6SvEvTacMmp16tm1KholMmp16Mmp16Mmp16tm1Khol
• short humerus_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0004351I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16Mmp14Mmp16Mmp16tm1KholMmp14tm1Hbh
• vomer bone hypoplasia_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0009900I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• postnatal lethality, incomplete penetrance_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0011086I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal long bone hypertrophic chondrocyte zone_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0000165I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• short femur_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0003109I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• abnormal compact bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003797I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• small cranium_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0005352I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• short humerus_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0004351I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• short femur_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003109I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• decreased bone ossification_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0020040I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• decreased body size_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0001265I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• small cranium_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0005352I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16Mmp14Mmp16Mmp16tm1KholMmp14tm1Hbh
• short snout_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000445I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• maxilla hypoplasia_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000457I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• short humerus_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0004351I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• decreased bone ossification_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0020040I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000166I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal cranium morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000438I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal cartilage morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000163I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal vomer bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000098I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal Meckel's cartilage morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0005587I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000166I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal compact bone morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0003797I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• abnormal mandible morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000458I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal neurocranium morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000074I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• short femur_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003109I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16tm1KholMmp14Mmp16tm1KholMmp14tm1Hbh
• abnormal long bone hypertrophic chondrocyte zone_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000165I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0000166I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• short snout_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000445I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• palatal shelves fail to meet at midline_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0009888I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal chondrocyte morphology_Mmp14<tm1Hbh>/Mmp14<+>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0000166I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14Mmp16tm1KholMmp16Mmp14Mmp16Mmp16tm1KholMmp14tm1Hbh
• abnormal long bone epiphyseal plate proliferative zone_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003662I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal long bone epiphyseal plate proliferative zone_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0003662I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• absent palatine bone_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0004476I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• short limbs_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0000547I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• neonatal lethality, complete penetrance_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0011087I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• abnormal facial morphology_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<tm1Khol>
  http://metadb.riken.jp/0003743I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16tm1KholMmp14tm1HbhMmp16tm1Khol
• decreased bone ossification_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0020040I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh
• small cranium_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>
  http://metadb.riken.jp/0005352I129P2OlaHsdMmp14tm1HbhMmp14tm1HbhMmp14tm1Hbh
• short humerus_Mmp14<tm1Hbh>/Mmp14<tm1Hbh>,Mmp16<tm1Khol>/Mmp16<+>
  http://metadb.riken.jp/0004351I129P2OlaHsd129S6SvEvTacMmp14tm1HbhMmp14tm1HbhMmp16tm1KholMmp16Mmp16Mmp16tm1KholMmp14tm1Hbh

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD10974
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10974