Ruben. Vidal, et.al., Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18171923

Ruben. Vidal, et.al., Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848965

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/db/mgi_rdf/MGI:3848965

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0002083B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• Purkinje cell degeneration_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0000876B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• decreased survivor rate_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0008770B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• neuronal intranuclear inclusions_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0004191B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal iron homeostasis_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0005637B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• abnormal grooming behavior_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0001440B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• neuronal intranuclear inclusions_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0004191B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• premature death_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0002083B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• lordosis_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0000162B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal Purkinje cell morphology_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0000877B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal gait_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0001406B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal iron homeostasis_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0005637B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal cerebellar granule layer morphology_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0000886B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• abnormal cerebellar granule cell morphology_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0004098B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• decreased survivor rate_Tg(Prnp-FTL*)4Ruvi/0
  http://metadb.riken.jp/0008770B6C3FeTgPrnpFTL4RuviTgPrnpFTL4Ruvi0TgPrnpFTL4Ruvi
• hunched posture_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0001505B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• limb grasping_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0001513B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• impaired coordination_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0001405B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi
• tremors_Tg(Prnp-FTL*)4Ruvi/Tg(Prnp-FTL*)4Ruvi
  http://metadb.riken.jp/0000745B6C3FeTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4RuviTgPrnpFTL4Ruvi