Kei. Hori, et.al., A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling., Genes & development, 2008, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/18198335

Kei. Hori, et.al., A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling., Genes & development, 2008, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax7-cre/ERT2)1Cbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:3774422
• Rbpj<tm1.1Hon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3807508

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax7-cre/ERT2)1Cbm
  http://metadb.riken.jp/db/mgi_rdf/MGI:3774422
• Rbpj<tm1.1Hon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3807508

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neural tube morphology_Rbpj<tm1Hon>/Rbpj<tm1.1Hon>,Tg(Pax7-cre/ERT2)1Cbm/0
  http://metadb.riken.jp/0002151I129P2OlaHsdBALBcJRbpjtm1HonRbpjtm11HonTgPax7creERT21Cbm0Rbpjtm1HonTgPax7creERT21CbmRbpjtm11Hon
• abnormal spinal cord interneuron morphology_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0004100I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• loss of GABAergic neurons_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0003246I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• abnormal neuron differentiation_Rbpj<tm1Hon>/Rbpj<tm1.1Hon>,Tg(Pax7-cre/ERT2)1Cbm/0
  http://metadb.riken.jp/0009937I129P2OlaHsdBALBcJRbpjtm1HonRbpjtm11HonTgPax7creERT21Cbm0Rbpjtm1HonTgPax7creERT21CbmRbpjtm11Hon
• absent pancreas_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0003655I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• decreased neuronal precursor cell number_Rbpj<tm1Hon>/Rbpj<tm1.1Hon>,Tg(Pax7-cre/ERT2)1Cbm/0
  http://metadb.riken.jp/0004981I129P2OlaHsdBALBcJRbpjtm1HonRbpjtm11HonTgPax7creERT21Cbm0Rbpjtm1HonTgPax7creERT21CbmRbpjtm11Hon
• abnormal neural tube morphology_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0002151I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• loss of GABAergic neurons_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0003246I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• abnormal neural tube morphology_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0002151I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• abnormal neuron differentiation_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0009937I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• neonatal lethality, complete penetrance_Ptf1a<tm1.1(cre)Cvw>/Ptf1a<tm1.1(cre)Cvw>
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJPtf1atm11creCvwPtf1atm11creCvwPtf1atm11creCvw
• abnormal neuron differentiation_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0009937I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• abnormal neural tube morphology_Gt(ROSA)26Sor<tm1(MAML1)Wsp>/Gt(ROSA)26Sor<+>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0002151NSGtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3GtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3
• loss of GABAergic neurons_Rbpj<tm1Hon>/Rbpj<tm1.1Hon>,Tg(Pax7-cre/ERT2)1Cbm/0
  http://metadb.riken.jp/0003246I129P2OlaHsdBALBcJRbpjtm1HonRbpjtm11HonTgPax7creERT21Cbm0Rbpjtm1HonTgPax7creERT21CbmRbpjtm11Hon
• small cerebellum_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0000852I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• absent pancreas_Ptf1a<tm1.1(cre)Cvw>/Ptf1a<tm1.1(cre)Cvw>
  http://metadb.riken.jp/0003655I129S1Sv129X1SvJPtf1atm11creCvwPtf1atm11creCvwPtf1atm11creCvw
• abnormal glutaminergic neuron morphology_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0003247I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• abnormal spinal cord dorsal horn morphology_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0006282I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• decreased neuronal precursor cell number_Gt(ROSA)26Sor<tm1(MAML1)Wsp>/Gt(ROSA)26Sor<+>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0004981NSGtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3GtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3
• abnormal glutaminergic neuron morphology_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0003247I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• decreased neuronal precursor cell number_Pax3<tm1(cre)Joe>/Pax3<+>,Rbpj<tm1Hon>/Rbpj<tm1Hon>
  http://metadb.riken.jp/0004981I129P2OlaHsdPax3tm1creJoePax3Rbpjtm1HonRbpjtm1HonPax3tm1creJoeRbpjtm1HonPax3
• loss of glutamate neurons_Gt(ROSA)26Sor<tm1(MAML1)Wsp>/Gt(ROSA)26Sor<+>,Pax3<tm1(cre)Joe>/Pax3<+>
  http://metadb.riken.jp/0003248NSGtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3GtROSA26Sortm1MAML1WspGtROSA26SorPax3tm1creJoePax3
• abnormal glutaminergic neuron morphology_Rbpj<tm1Hon>/Rbpj<tm1.1Hon>,Tg(Pax7-cre/ERT2)1Cbm/0
  http://metadb.riken.jp/0003247I129P2OlaHsdBALBcJRbpjtm1HonRbpjtm11HonTgPax7creERT21Cbm0Rbpjtm1HonTgPax7creERT21CbmRbpjtm11Hon
• abnormal cerebellar granule layer morphology_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0000886I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• decreased neuronal precursor cell number_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0004981I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd
• neonatal lethality, complete penetrance_Ptf1a<tm2Macd>/Ptf1a<tm2Macd>
  http://metadb.riken.jp/0011087I129S6SvEvTacPtf1atm2MacdPtf1atm2MacdPtf1atm2Macd