Pengfei. Wang, et.al., Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice., Molecular and cellular biology, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18212049

Pengfei. Wang, et.al., Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice., Molecular and cellular biology, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdc73<tm1Btt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794030
• Cdc73<tm1.1Btt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794032
• Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794028

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• small liver_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000601I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small heart_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002188I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased cell proliferation_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000352I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased subcutaneous adipose tissue amount_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008844I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small spleen_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000692I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased embryo size_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001698I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased skeletal muscle mass_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0004819I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• hepatic necrosis_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001654I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• ascites_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005324I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• weight loss_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001263I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small seminal vesicle_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001157I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased pulmonary respiratory rate_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005574I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small lung_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003641I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small stomach_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002691I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small kidney_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002989I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small testis_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001147I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• abnormal digestive system morphology_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000462I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• small salivary gland_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0000618I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• failure of embryo implantation_Cdc73<Gt(RRE190)Byg>/Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/0001728I129P2OlaHsdCdc73GtRRE190BygCdc73GtRRE190BygCdc73GtRRE190Byg
• abnormal nervous system development_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003861I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• hypoactivity_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001402I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• premature death_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• increased fibroblast apoptosis_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0013501I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• renal necrosis_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0003946I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• absent inner cell mass proliferation_Cdc73<Gt(RRE190)Byg>/Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/0012114I129P2OlaHsdCdc73GtRRE190BygCdc73GtRRE190BygCdc73GtRRE190Byg
• abnormal reflex_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0001961I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• decreased abdominal adipose tissue amount_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008853I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• absent trophectoderm cell proliferation_Cdc73<Gt(RRE190)Byg>/Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/0012118I129P2OlaHsdCdc73GtRRE190BygCdc73GtRRE190BygCdc73GtRRE190Byg
• embryonic lethality before implantation, complete penetrance_Cdc73<Gt(RRE190)Byg>/Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/0011094I129P2OlaHsdCdc73GtRRE190BygCdc73GtRRE190BygCdc73GtRRE190Byg
• increased apoptosis_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0006042I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• abnormal gland physiology_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0002164I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt
• embryonic lethality, complete penetrance_Cdc73<tm1.1Btt>/Cdc73<tm1.1Btt>
  http://metadb.riken.jp/0011092I129S4SvJaeBALBcJCdc73tm11BttCdc73tm11BttCdc73tm11Btt
• prenatal lethality, complete penetrance_Cdc73<tm1Btt>/Cdc73<tm1Btt>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0011091I129S4SvJaeC57BL6CBACdc73tm1BttCdc73tm1BttTgCAGcreEsr15Amc0TgCAGcreEsr15AmcCdc73tm1Btt

class

http://purl.org/net/cito/citesAsAuthority

• Cdc73<tm1Btt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794030
• Cdc73<tm1.1Btt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794032
• Cdc73<Gt(RRE190)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794028

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD07707
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07707