Thomas S. Lisse, et.al., ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta., PLoS genetics, 2008, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/18248096

Thomas S. Lisse, et.al., ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta., PLoS genetics, 2008, 4

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<Aga2>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769585

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• fragile skeleton_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000061IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased body weight_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001262IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• increased circulating parathyroid hormone level_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0002904IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• embryonic lethality, complete penetrance_Col1a1<Aga2>/Col1a1<Aga2>
  http://metadb.riken.jp/0011092IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Aga2Col1a1Aga2
• abnormal fibula morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0002187IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased body length_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001258IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal osteoblast morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0004986IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• kyphoscoliosis_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000069IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• hemorrhage_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001914IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal ischium morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0004507IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal neurocranium morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000074IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal femur morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000559IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal osteoblast physiology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0005006IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal enzyme/coenzyme level_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0005319IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal pubis morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0004506IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• postnatal lethality, incomplete penetrance_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0011086IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal adipose tissue distribution_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000013IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• short femur_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0003109IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased circulating alkaline phosphatase level_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0002966IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal skeleton morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0005508IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased litter size_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001935IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased diameter of femur_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0008152IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased bone mineral content_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0010124IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal dermal layer morphology_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001243IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased body size_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001265IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• decreased bone mineral density_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0000063IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal compact bone lamellar structure_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0010970IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• abnormal hormone level_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0003953IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2
• intracranial hemorrhage_Col1a1<Aga2>/Col1a1<+>
  http://metadb.riken.jp/0001915IC3HeBFeJC57BL6JCol1a1Aga2Col1a1Col1a1Col1a1Aga2

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<Aga2>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769585