Sekiya. Shibazaki, et.al., Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1., Human molecular genetics, 2008, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/18263604

Sekiya. Shibazaki, et.al., Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1., Human molecular genetics, 2008, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pkd1<tm2Som>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3793791
• Pkd1<tm2.1Som>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3793792
• Tg(Pkhd1-cre)1Igr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794109

class

http://purl.org/net/cito/citesAsAuthority

• Pkd1<tm2Som>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3793791
• Pkd1<tm2.1Som>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3793792
• Tg(Pkhd1-cre)1Igr
  http://metadb.riken.jp/db/mgi_rdf/MGI:3794109

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased blood urea nitrogen level_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005565IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• postnatal lethality, complete penetrance_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0011085IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• increased circulating phosphate level_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0001566IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• kidney cysts_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Pkhd1-cre)1Igr/0
  http://metadb.riken.jp/0003675IC57BL6SJLPkd1tm2SomPkd1tm2SomTgPkhd1cre1Igr0TgPkhd1cre1IgrPkd1tm2Som
• increased circulating phosphate level_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0001566IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• abnormal kidney morphology_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Pkhd1-cre)1Igr/0
  http://metadb.riken.jp/0002135IC57BL6SJLPkd1tm2SomPkd1tm2SomTgPkhd1cre1Igr0TgPkhd1cre1IgrPkd1tm2Som
• postnatal lethality, complete penetrance_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0011085IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• abnormal kidney morphology_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0002135IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• abnormal kidney morphology_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0002135IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• polycystic kidney_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0008528IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• increased circulating cholesterol level_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005178IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• increased circulating cholesterol level_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005178IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• polycystic kidney_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0008528IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• increased kidney weight_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0003917IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• embryonic lethality during organogenesis_Pkd1<tm2.1Som>/Pkd1<tm2.1Som>
  http://metadb.riken.jp/0006207IC57BL6FVBNSJLPkd1tm21SomPkd1tm21SomPkd1tm21Som
• decreased circulating glucose level_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005560IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• kidney failure_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0003606IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• increased kidney weight_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0003917IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• decreased circulating glucose level_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005560IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som
• kidney failure_Pkd1<tm2Som>/Pkd1<tm2.1Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0003606IC57BL6ICRSJLPkd1tm2SomPkd1tm21SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2SomPkd1tm21Som
• increased blood urea nitrogen level_Pkd1<tm2Som>/Pkd1<tm2Som>,Tg(Cdh16-cre)91Igr/0
  http://metadb.riken.jp/0005565IC57BL6ICRSJLPkd1tm2SomPkd1tm2SomTgCdh16cre91Igr0TgCdh16cre91IgrPkd1tm2Som