Weiwei. Fan, et.al., A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations., Science (New York, N.Y.), 2008, 319

http://rdf.ncbi.nlm.nih.gov/pubmed/18276892

Weiwei. Fan, et.al., A mouse model of mitochondrial disease reveals germline selection against severe mtDNA mutations., Science (New York, N.Y.), 2008, 319

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• mt-Nd6<m2Dwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3777242
• mt-Nd6<m1Dwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3777241

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardial fiber physiology_mt-Co1<m1Jiha>,mt-Nd6<m1Dwa>,mt-Nd6<m2Dwa>
  http://metadb.riken.jp/0004215IC3HAnC57BL6JMmdomesticusmtCo1m1JihamtNd6m1DwamtNd6m2DwamtCo1m1JihamtNd6m1DwamtNd6m2Dwa
• myocardial fiber degeneration_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0004566IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal myocardial fiber morphology_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0000278IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• cardiac interstitial fibrosis_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0005608IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal mitochondrial ATP synthesis coupled electron transport_mt-Co1<m1Jiha>,mt-Nd6<m1Dwa>,mt-Nd6<m2Dwa>
  http://metadb.riken.jp/0010956IC3HAnC57BL6JMmdomesticusmtCo1m1JihamtNd6m1DwamtNd6m2DwamtCo1m1JihamtNd6m1DwamtNd6m2Dwa
• abnormal blood vessel morphology_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0001614IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal heart ventricle pressure_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0008775IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• cardiomyopathy_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0005330IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal mitochondrial ATP synthesis coupled electron transport_mt-Nd6<m1Dwa>
  http://metadb.riken.jp/0010956IC3HAnC57BL6JMmdomesticusmtNd6m1DwamtNd6m1Dwa
• myopathy_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0000751IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• heart inflammation_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0001853IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal heart morphology_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0000266IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• edema_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0001785IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha
• abnormal heart left ventricle morphology_mt-Co1<m1Jiha>
  http://metadb.riken.jp/0003921IC57BL6JMmdomesticusmtCo1m1JihamtCo1m1Jiha

class

http://purl.org/net/cito/citesAsAuthority

• mt-Nd6<m2Dwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3777242
• mt-Nd6<m1Dwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3777241