Fiona M. Laird, et.al., Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18305234

Fiona M. Laird, et.al., Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-DCTN1*G59S)M2Pcw
  http://metadb.riken.jp/db/mgi_rdf/MGI:5308396

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal axon morphology_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0005404IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• tremors_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0000745IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• abnormal motor neuron morphology_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0000937IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• limb grasping_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0001513IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• astrocytosis_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0003354IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• axon degeneration_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0005405IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• muscular atrophy_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0002269IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• progressive muscle weakness_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0000748IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• neuronal cytoplasmic inclusions_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0011975IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• abnormal gait_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0001406IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• abnormal neuromuscular synapse morphology_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0001053IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• paralysis_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0000753IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• abnormal skeletal muscle fiber morphology_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0003084IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• chromatolysis_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0002883IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• weight loss_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0001263IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• decreased motor neuron number_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0000939IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• abnormal ventral spinal root morphology_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0003993IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw
• decreased grip strength_Tg(Thy1-DCTN1*G59S)M2Pcw/?
  http://metadb.riken.jp/0010053IC57BL6SJLTgThy1DCTN1G59SM2PcwTgThy1DCTN1G59SM2Pcw

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-DCTN1*G59S)M2Pcw
  http://metadb.riken.jp/db/mgi_rdf/MGI:5308396