Dick. Jaarsma, et.al., Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18305242

Dick. Jaarsma, et.al., Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785090
• Tg(Thy1-SOD1*G93A)T1Hgrd
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785266

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785090
• Tg(Thy1-SOD1*G93A)T1Hgrd
  http://metadb.riken.jp/db/mgi_rdf/MGI:3785266

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• muscle weakness_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000747IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• muscle weakness_Tg(SOD1*G93A)<dl>1Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000747IC57BL6CBAFVBSJLTgSOD1G93Adl1Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD1G93Adl1Gur
• muscle weakness_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0000747IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• progressive muscle weakness_Tg(SOD1*G93A)<dl>1Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000748IC57BL6CBAFVBSJLTgSOD1G93Adl1Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD1G93Adl1Gur
• progressive muscle weakness_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000748IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• progressive muscle weakness_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0000748IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
他34件を見る
• progressive muscle weakness_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0000748IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• paralysis_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000753IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• decreased motor neuron number_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000939IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• decreased motor neuron number_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000939IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• decreased motor neuron number_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0000939IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• abnormal oligodendrocyte morphology_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000953IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• abnormal oligodendrocyte morphology_Tg(SOD1)2Gur/0
  http://metadb.riken.jp/0000953IC57BL6CBASJLTgSOD12Gur0TgSOD12Gur
• abnormal spinal cord morphology_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0000955IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal spinal cord morphology_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0000955IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• abnormal innervation pattern to muscle_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001052IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• abnormal neuromuscular synapse morphology_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001053IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal neuromuscular synapse morphology_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0001053IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• weight loss_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001263IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• weight loss_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0001263IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• impaired coordination_Tg(SOD1*G93A)<dl>1Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001405IC57BL6CBAFVBSJLTgSOD1G93Adl1Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD1G93Adl1Gur
• impaired coordination_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001405IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• impaired coordination_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0001405IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• impaired coordination_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0001405IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• abnormal grip strength_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001515IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal grip strength_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0001515IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• abnormal motor coordination/ balance_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0001516IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal motor coordination/ balance_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0001516IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• premature death_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0002083IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• abnormal brain morphology_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0002152IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal brain morphology_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0002152IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• gliosis_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0002183IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• neuron degeneration_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0003224IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• neuron degeneration_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0003224IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• astrocytosis_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0003354IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd
• astrocytosis_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0003354IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• abnormal mitochondrion morphology_Tg(SOD1*G93A)<dl>1Gur/0
  http://metadb.riken.jp/0006035IC57BL6CBASJLTgSOD1G93Adl1Gur0TgSOD1G93Adl1Gur
• abnormal dendrite morphology_Tg(SOD1)2Gur/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0008143IC57BL6CBAFVBSJLTgSOD12Gur0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgSOD12Gur
• abnormal neurite morphology_Tg(Thy1-SOD1*G93A)T1Hgrd/0,Tg(Thy1-SOD1*G93A)T3Hgrd/0
  http://metadb.riken.jp/0008415IC57BL6CBAFVBTgThy1SOD1G93AT1Hgrd0TgThy1SOD1G93AT3Hgrd0TgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT1Hgrd
• abnormal neurite morphology_Tg(Thy1-SOD1*G93A)T3Hgrd/Tg(Thy1-SOD1*G93A)T3Hgrd
  http://metadb.riken.jp/0008415IC57BL6CBAFVBTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3HgrdTgThy1SOD1G93AT3Hgrd