Chad K. Heazlewood, et.al., Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis., PLoS medicine, 2008, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/18318598

Chad K. Heazlewood, et.al., Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis., PLoS medicine, 2008, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Muc2<eey>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5471473

class

http://purl.org/net/cito/citesAsAuthority

• Muc2<eey>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5471473

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• melena_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0003292C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• ileum inflammation_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0009482C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased leukocyte cell number_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000218C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• intestinal ulcer_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000512C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• decreased colon length_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0013956C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased tumor necrosis factor secretion_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008560C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased interferon-gamma secretion_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008566C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased endoplasmic reticulum stress_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0020354C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• premature death_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0002083C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased interferon-gamma secretion_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008566C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased tumor necrosis factor secretion_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008560C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased susceptibility to induced colitis_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008537C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• ileum inflammation_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0009482C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• abnormal intestinal goblet cell morphology_Muc2<wnn>/Muc2<+>
  http://metadb.riken.jp/0003449C57BL6Muc2wnnMuc2wnnMuc2Muc2Muc2wnn
• abnormal colon morphology_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0000495C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• abnormal digestive system physiology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0001663C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal enterocyte proliferation_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008883C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased lymphocyte cell number_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0005013C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• rectal hemorrhage_Muc2<wnn>/Muc2<+>
  http://metadb.riken.jp/0003293C57BL6Muc2wnnMuc2wnnMuc2Muc2Muc2wnn
• abnormal colon morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000495C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• dilated mitochondria_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0011632C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal endoplasmic reticulum morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0009378C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal intestinal goblet cell morphology_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0003449C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• abnormal intestinal goblet cell morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0003449C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased sensitivity to xenobiotic induced morbidity/mortality_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0009766C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal intestine morphology_Muc2<eey>/Muc2<wnn>
  http://metadb.riken.jp/0000477C57BL6Muc2eeyMuc2wnnMuc2eeyMuc2wnnMuc2eeyMuc2wnn
• increased susceptibility to induced colitis_Muc2<wnn>/Muc2<+>
  http://metadb.riken.jp/0008537C57BL6Muc2wnnMuc2wnnMuc2Muc2Muc2wnn
• rectal prolapse_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0000493C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• rectal prolapse_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000493C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• decreased hematocrit_Muc2<wnn>/Muc2<+>
  http://metadb.riken.jp/0000208C57BL6Muc2wnnMuc2wnnMuc2Muc2Muc2wnn
• decreased hematocrit_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000208C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal large intestine crypts of Lieberkuhn morphology_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0004842C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• dilated mitochondria_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0011632C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• melena_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0003292C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• abnormal intestinal mucosa morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0000511C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased interleukin-1 beta secretion_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008657C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• colitis_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0002816C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal mitochondrial crista morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0011635C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased enterocyte apoptosis_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008885C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased interleukin-13 secretion_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008672C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased susceptibility to weight loss_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0010180C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased susceptibility to induced colitis_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008537C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal mitochondrial crista morphology_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0011635C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• premature death_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0002083C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased leukocyte cell number_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0000218C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• increased enterocyte apoptosis_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008885C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased circulating triglyceride level_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0001552C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased endoplasmic reticulum stress_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0020354C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal endoplasmic reticulum morphology_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0009378C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey
• abnormal intestine physiology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0010155C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal large intestine crypts of Lieberkuhn morphology_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0004842C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• abnormal enterocyte proliferation_Muc2<wnn>/Muc2<wnn>
  http://metadb.riken.jp/0008883C57BL6Muc2wnnMuc2wnnMuc2wnnMuc2wnn
• increased interleukin-1 beta secretion_Muc2<eey>/Muc2<eey>
  http://metadb.riken.jp/0008657C57BL6Muc2eeyMuc2eeyMuc2eeyMuc2eey