Silke. Nuber, et.al., Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18322092

Silke. Nuber, et.al., Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-SNCA)0Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5512701

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased dopaminergic neuron number_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0011448IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• neuron degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0003224IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal long term spatial reference memory_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0008432IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal synaptic bouton morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0008571IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• decreased dopamine level_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0005643IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal substantia nigra pars reticulata morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0013218IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal motor coordination/ balance_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0001516IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• hippocampal neuron degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0000811IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• decreased neuronal precursor cell number_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0004981IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• impaired coordination_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0001405IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal substantia nigra morphology_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0000836IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• alpha-synuclein inclusion body_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0008493IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal motor learning_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0002804IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• hippocampus pyramidal cell degeneration_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0010014IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay
• abnormal neuron differentiation_Tg(Camk2a-tTA)1Mmay/0,Tg(tetO-SNCA)0Olri/0
  http://metadb.riken.jp/0009937IC57BL6TgCamk2atTA1Mmay0TgtetOSNCA0Olri0TgtetOSNCA0OlriTgCamk2atTA1Mmay

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-SNCA)0Olri
  http://metadb.riken.jp/db/mgi_rdf/MGI:5512701