Shu. Xing, et.al., Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice., Blood, 2008, 111

http://rdf.ncbi.nlm.nih.gov/pubmed/18334677

Shu. Xing, et.al., Transgenic expression of JAK2V617F causes myeloproliferative disorders in mice., Blood, 2008, 111

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Vav1-JAK2*V617F)AZjz
  http://metadb.riken.jp/db/mgi_rdf/MGI:5441310

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased hematocrit_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0002608IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• abnormal blood cell morphology/development_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0002429IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• decreased circulating erythropoietin level_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0011286IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• abnormal megakaryocyte progenitor cell morphology_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0002413IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased hemoglobin content_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0005564IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• thrombocytosis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0005505IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• enlarged spleen_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0000691IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased erythrocyte cell number_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0003131IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• spleen fibrosis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0011746IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased granulocyte number_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0000322IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased leukocyte cell number_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0000218IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• abnormal definitive hematopoiesis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0002123IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• myelofibrosis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0011747IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• abnormal blood homeostasis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0009642IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased spleen weight_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0004952IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• giant platelets_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0030025IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• increased megakaryocyte cell number_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0008254IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz
• microcytosis_Tg(Vav1-JAK2*V617F)AZjz/0
  http://metadb.riken.jp/0002813IC57BL6DBA2TgVav1JAK2V617FAZjz0TgVav1JAK2V617FAZjz

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Vav1-JAK2*V617F)AZjz
  http://metadb.riken.jp/db/mgi_rdf/MGI:5441310