Santhosh. Girirajan, et.al., Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response., Mammalian genome : official journal of the International Mammalian Genome Society, 2008, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/18343975

Santhosh. Girirajan, et.al., Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response., Mammalian genome : official journal of the International Mammalian Genome Society, 2008, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3784979

class

http://purl.org/net/cito/citesAsAuthority

• Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3784979

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• skin lesions_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001212I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• exophthalmos_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002750I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• enlarged spleen_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002020I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased B cell number_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0005014I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased metastatic potential_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001272I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased basal cell carcinoma incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0004208I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• emphysema_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001958I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• lymphoid hyperplasia_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000688I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased adenoma incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0010383I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• enlarged spleen_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• kidney cysts_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0003675I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal inflammatory response_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001845I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased susceptibility to infection_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002406I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• abnormal humoral immune response_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001800I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• kyphosis_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased prostate gland tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0010357I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased spleen white pulp amount_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008478I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased skin tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0010300I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• hydroencephaly_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001891I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• abnormal fear/anxiety-related behavior_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002065I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased prostate gland tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0010357I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• abnormal splenic cell ratio_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008826I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal cornea morphology_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001312I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• hyperactivity_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001399I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• kyphosis_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• conjunctivitis_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001852I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased mammary gland tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• malocclusion_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000120I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased susceptibility to bacterial infection_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0002412I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• focal hair loss_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000418I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased susceptibility to infection_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0002406I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal spleen morphology_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000689I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal fear/anxiety-related behavior_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0002065I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• dermatitis_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001194I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal spleen periarteriolar lymphoid sheath morphology_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0002358I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased leukocyte cell number_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0000218I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased CD4-positive, alpha beta T cell number_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008074I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• thrombocytopenia_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0003179I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased inflammatory response_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001846I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• hemorrhage_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001914I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal immune system physiology_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001790I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0002020I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• spontaneous skin ulceration_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001209I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• abnormal spleen B cell follicle morphology_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008470I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• skin lesions_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001212I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased CD8-positive, alpha-beta T cell number_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008078I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• abnormal lymph node cell ratio_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008828I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased vertical activity_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002574I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased lung tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008014I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased ovary tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0008000I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased T cell number_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0005015I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• spontaneous skin ulceration_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001209I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• hydroencephaly_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0001891I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• increased lung tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0008014I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• abnormal eye distance/ position_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0001299I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased total body fat amount_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0010024I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2
• increased skin tumor incidence_Tom1l2<Gt(XG909)Byg>/Tom1l2<Gt(XG909)Byg>
  http://metadb.riken.jp/0010300I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2GtXG909BygTom1l2GtXG909Byg
• ovary cysts_Tom1l2<Gt(XG909)Byg>/Tom1l2<+>
  http://metadb.riken.jp/0002016I129P2OlaHsdC57BL6JTom1l2GtXG909BygTom1l2Tom1l2GtXG909BygTom1l2

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09148
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09148