Jose R. Bayascas, et.al., Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance., Molecular and cellular biology, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18347057

Jose R. Bayascas, et.al., Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance., Molecular and cellular biology, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pdpk1<tm1Dral>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3795190

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0005293B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• small spleen_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0000692B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• small testis_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0001147B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• insulin resistance_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0005331B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• abnormal adrenal gland zona fasciculata morphology_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0008294B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• small pancreas_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0004247B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• abnormal kidney size_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0002706B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• increased circulating insulin level_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0002079B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• pancreatic islet hypoplasia_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0009169B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• decreased brain size_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0000774B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• pancreatic islet hyperplasia_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0005491B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral
• decreased body weight_Pdpk1<tm1Dral>/Pdpk1<tm1Dral>
  http://metadb.riken.jp/0001262B6129P2Pdpk1tm1DralPdpk1tm1DralPdpk1tm1DralPdpk1tm1Dral

class

http://purl.org/net/cito/citesAsAuthority

• Pdpk1<tm1Dral>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3795190