Jisen. Huai, et.al., Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/18362329

Jisen. Huai, et.al., Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tpp2<tm1Gnie>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783749
• Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783750

class

http://purl.org/net/cito/citesAsAuthority

• Tpp2<tm1Gnie>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783749
• Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3783750

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immune system organ morphology_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0002722I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• increased T cell apoptosis_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0006413I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• thymus atrophy_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0003644I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• abnormal cell cycle_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0003077I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• decreased CD8-positive, alpha-beta T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0008079I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• disheveled coat_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0001511I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• decreased double-positive T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0005092I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• increased spleen red pulp amount_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0008476I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• premature death_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0002083I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• decreased T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0005018I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• focal hair loss_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0000418I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• enlarged spleen_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0000691I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• increased T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0005015I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• abnormal immune system cell morphology_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0000716I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• premature aging_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0003786I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• increased double-negative T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0005090I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• increased single-positive T cell number_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0008082I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• extramedullary hematopoiesis_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0000240I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• weight loss_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0001263I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• abnormal cytotoxic T cell physiology_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0005078I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• early cellular replicative senescence_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0008008I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• abnormal spleen morphology_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0000689I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie
• abnormal splenic cell ratio_Tpp2<tm1.1Gnie>/Tpp2<tm1.1Gnie>
  http://metadb.riken.jp/0008826I129S6SvEvTacC57BL6Tpp2tm11GnieTpp2tm11GnieTpp2tm11Gnie

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05604
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05604