Craig D. Jude, et.al., Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors., Cell stem cell, 2007, 1

http://rdf.ncbi.nlm.nih.gov/pubmed/18371366

Craig D. Jude, et.al., Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors., Cell stem cell, 2007, 1

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kmt2a<tm1.1Erns>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3839794
• Kmt2a<tm1.2Erns>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3839795

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased bone marrow cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000333I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• decreased erythroid progenitor cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>
  http://metadb.riken.jp/0008973I129S2SvPasC57BL6SJLKmt2atm11ErnsKmt2atm11ErnsKmt2atm11Erns
• decreased common myeloid progenitor cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>
  http://metadb.riken.jp/0008813I129S2SvPasC57BL6SJLKmt2atm11ErnsKmt2atm11ErnsKmt2atm11Erns
• embryonic lethality, complete penetrance_Kmt2a<tm1Sjk>/Kmt2a<tm1Sjk>
  http://metadb.riken.jp/0011092I129S2SvPasC3HC57BL6Kmt2atm1SjkKmt2atm1SjkKmt2atm1Sjk
• abnormal common lymphocyte progenitor cell morphology_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008249I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• embryonic lethality during organogenesis, complete penetrance_Kmt2a<tm1Sjk>/Kmt2a<tm1.2Erns>
  http://metadb.riken.jp/0011098I129S2SvPasC57BL6FVBNKmt2atm1SjkKmt2atm12ErnsKmt2atm1SjkKmt2atm12Erns
• decreased erythroid progenitor cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008973I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• premature death_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• decreased common myeloid progenitor cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008813I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• abnormal hematopoietic stem cell morphology_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004808I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• abnormal definitive hematopoiesis_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>
  http://metadb.riken.jp/0002123I129S2SvPasC57BL6SJLKmt2atm11ErnsKmt2atm11ErnsKmt2atm11Erns
• abnormal definitive hematopoiesis_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002123I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• decreased hematopoietic stem cell number_Kmt2a<tm1.1Erns>/Kmt2a<tm1.1Erns>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004810I129S2SvPasC57BL6CBASJLKmt2atm11ErnsKmt2atm11ErnsTgMx1cre1Cgn0Kmt2atm11ErnsTgMx1cre1Cgn
• embryonic lethality during organogenesis, complete penetrance_Kmt2a<tm1.2Erns>/Kmt2a<tm1.2Erns>
  http://metadb.riken.jp/0011098I129S2SvPasC57BL6FVBNKmt2atm12ErnsKmt2atm12ErnsKmt2atm12Erns

class

http://purl.org/net/cito/citesAsAuthority

• Kmt2a<tm1.1Erns>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3839794
• Kmt2a<tm1.2Erns>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3839795