Vincent C H. Lui, et.al., Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in mice., Gastroenterology, 2008, 134

http://rdf.ncbi.nlm.nih.gov/pubmed/18395091

Vincent C H. Lui, et.al., Perturbation of hoxb5 signaling in vagal neural crests down-regulates ret leading to intestinal hypoganglionosis in mice., Gastroenterology, 2008, 134

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-en/Hoxb5,-EGFP)#Vchl
  http://metadb.riken.jp/db/mgi_rdf/MGI:5749814
• Tg(Hoxb3-cre)1Pkht
  http://metadb.riken.jp/db/mgi_rdf/MGI:3796197

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• distended abdomen_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0001270NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• aganglionic megacolon_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0002926NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal enteric neural crest cell migration_Tg(CAG-Bgeo/ALPP)1Lbe/0,Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0013006I129S1Sv129X1SvJTgCAGBgeoALPP1Lbe0TgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGBgeoALPP1LbeTgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal ileum morphology_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0002581NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal colon morphology_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0000495NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• postnatal growth retardation_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0001732NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• postnatal lethality, incomplete penetrance_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0011086NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• enlarged duodenum_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0011882NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• distended jejunum_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0011503NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal enteric neural crest cell migration_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0013006NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• ileum atresia_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0011879NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal enteric neuron morphology_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0001046NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht
• abnormal intestinal transit time_Tg(CAG-en/Hoxb5,-EGFP)#Vchl/0,Tg(Hoxb3-cre)1Pkht/0
  http://metadb.riken.jp/0006001NSTgCAGenHoxb5EGFPVchl0TgHoxb3cre1Pkht0TgCAGenHoxb5EGFPVchlTgHoxb3cre1Pkht

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-en/Hoxb5,-EGFP)#Vchl
  http://metadb.riken.jp/db/mgi_rdf/MGI:5749814
• Tg(Hoxb3-cre)1Pkht
  http://metadb.riken.jp/db/mgi_rdf/MGI:3796197