Wei. Guo, et.al., Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation., Nature, 2008, 453

http://rdf.ncbi.nlm.nih.gov/pubmed/18463637

Wei. Guo, et.al., Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation., Nature, 2008, 453

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased acute lymphoblastic leukemia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0010336I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• abnormal definitive hematopoiesis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0002123I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• increased leukocyte cell number_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000218I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• abnormal blood vessel morphology_Ctnnb1<tm2Kem>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0001614I129S1Sv129S4SvJae129X1SvJBALBcC57BL6FVBNCtnnb1tm2KemCtnnb1Ptentm1HwuPtentm1HwuTgCdh5cre7Mlia0Ptentm1HwuCtnnb1tm2KemTgCdh5cre7MliaCtnnb1
• enlarged spleen_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000691I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• increased acute promyelocytic leukemia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0004049I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• embryonic lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0011092I129S1Sv129S4SvJae129X1SvJBALBcC57BL6FVBNCtnnb1tm2KemCtnnb1tm2KemPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0Ptentm1HwuTgCdh5cre7MliaCtnnb1tm2Kem
• enlarged thymus_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000709I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• premature death_Ctnnb1<tm2Kem>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0002083I129S1Sv129S4SvJae129X1SvJBALBcC57BL6FVBNCtnnb1tm2KemCtnnb1Ptentm1HwuPtentm1HwuTgCdh5cre7Mlia0Ptentm1HwuCtnnb1tm2KemTgCdh5cre7MliaCtnnb1
• enlarged liver_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000599I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• enlarged lymph nodes_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000702I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu
• abnormal definitive hematopoiesis_Ctnnb1<tm2Kem>/Ctnnb1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0002123I129S1Sv129S4SvJae129X1SvJBALBcC57BL6FVBNCtnnb1tm2KemCtnnb1Ptentm1HwuPtentm1HwuTgCdh5cre7Mlia0Ptentm1HwuCtnnb1tm2KemTgCdh5cre7MliaCtnnb1
• increased neutrophil cell number_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0
  http://metadb.riken.jp/0000219I129S4SvJaeBALBcC57BL6FVBNPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0TgCdh5cre7MliaPtentm1Hwu