Alberto J. Schuhmacher, et.al., A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition., The Journal of clinical investigation, 2008, 118

http://rdf.ncbi.nlm.nih.gov/pubmed/18483625

Alberto J. Schuhmacher, et.al., A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition., The Journal of clinical investigation, 2008, 118

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hras<tm1Xbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3803581
• Hras<tm2Xbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3803587

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circulating protein level_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0005416I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal aorta tunica media morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0009873I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• decreased urine creatinine level_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0011471I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal blood vessel morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0001614I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal branching of the mammary ductal tree_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000662I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal facial morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0003743I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• short premaxilla_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000091I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• no abnormal phenotype detected_Hras<tm1Xbr>/Hras<tm1Xbr>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJC57BL6Hrastm1XbrHrastm1XbrHrastm1Xbr
• heart right ventricle hypertrophy_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000276I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal frontal bone morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000107I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• increased heart ventricle size_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0008772I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal cranium morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000438I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• increased systemic arterial diastolic blood pressure_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0006143I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• renal fibrosis_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0003985I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• increased systemic arterial blood pressure_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0002842I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• enlarged heart atrium_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0008725I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• hypertension_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000231I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• increased systemic arterial systolic blood pressure_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0006144I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal heart morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000266I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal snout morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000443I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• short maxilla_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000097I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• increased mammary adenocarcinoma incidence_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0001883I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• mammary gland hyperplasia_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000630I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal mammary gland development_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0000628I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal vibrissa follicle morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0010234I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• heart left ventricle hypertrophy_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0002625I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• abnormal lip morphology_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0003769I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• enlarged aortic valve_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0010591I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr
• short zygomatic bone_Hras<tm2Xbr>/Hras<tm2Xbr>
  http://metadb.riken.jp/0003108I129S1Sv129X1SvJC57BL6FVBNHrastm2XbrHrastm2XbrHrastm2Xbr

class

http://purl.org/net/cito/citesAsAuthority

• Hras<tm1Xbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3803581
• Hras<tm2Xbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3803587