Stephan E. Lehnart, et.al., Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice., The Journal of clinical investigation, 2008, 118

http://rdf.ncbi.nlm.nih.gov/pubmed/18483626

Stephan E. Lehnart, et.al., Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice., The Journal of clinical investigation, 2008, 118

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ryr2<tm2Amks>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802940

class

http://purl.org/net/cito/citesAsAuthority

• Ryr2<tm2Amks>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3802940

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, incomplete penetrance_Ryr2<tm2Amks>/Ryr2<tm2Amks>
  http://metadb.riken.jp/0011109B6CgRyr2tm2AmksRyr2tm2AmksRyr2tm2AmksRyr2tm2Amks
• ventricular tachycardia_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0008950B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• tonic-clonic seizures_Ryr2<tm2Amks>/Ryr2<tm2Amks>
  http://metadb.riken.jp/0003997B6CgRyr2tm2AmksRyr2tm2AmksRyr2tm2AmksRyr2tm2Amks
• increased susceptibility to pharmacologically induced seizures_Ryr2<tm2Amks>/Ryr2<tm2Amks>
  http://metadb.riken.jp/0002906B6CgRyr2tm2AmksRyr2tm2AmksRyr2tm2AmksRyr2tm2Amks
• fetal growth retardation_Ryr2<tm2Amks>/Ryr2<tm2Amks>
  http://metadb.riken.jp/0004201B6CgRyr2tm2AmksRyr2tm2AmksRyr2tm2AmksRyr2tm2Amks
• decreased survivor rate_Ryr2<tm2Amks>/Ryr2<tm2Amks>
  http://metadb.riken.jp/0008770B6CgRyr2tm2AmksRyr2tm2AmksRyr2tm2AmksRyr2tm2Amks
• increased response of heart to induced stress_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0004485B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• abnormal brain wave pattern_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0004994B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• tonic-clonic seizures_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0003997B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• increased sensitivity to induced morbidity/mortality_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0009763B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• increased susceptibility to pharmacologically induced seizures_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0002906B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks
• abnormal myocardial fiber physiology_Ryr2<tm2Amks>/Ryr2<+>
  http://metadb.riken.jp/0004215B6CgRyr2tm2AmksRyr2tm2AmksRyr2Ryr2Ryr2tm2Amks