Peijun P. Shi, et.al., Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2., American journal of physiology. Renal physiology, 2008, 295

http://rdf.ncbi.nlm.nih.gov/pubmed/18524855

Peijun P. Shi, et.al., Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2., American journal of physiology. Renal physiology, 2008, 295

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3846431
• Nedd4l<tm1.1Blyg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3846430

class

http://purl.org/net/cito/citesAsAuthority

• Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3846431
• Nedd4l<tm1.1Blyg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3846430

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased left ventricle weight_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0003915I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• increased fluid intake_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0011941I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• decreased cardiac muscle contractility_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0005140I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• decreased heart rate_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0005333I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• hypertension_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0000231I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• polyuria_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0001762I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• increased circulating sodium level_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0005633I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• increased circulating aldosterone level_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0002666I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• abnormal systemic arterial blood pressure_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0000230I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• salt-sensitive hypertension_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0004217I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• increased circulating potassium level_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0005627I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg
• decreased intestinal epithelial sodium ion transmembrane transport_Nedd4l<tm1.2Blyg>/Nedd4l<tm1.2Blyg>
  http://metadb.riken.jp/0014206I129X1SvJC57BL6JNedd4ltm12BlygNedd4ltm12BlygNedd4ltm12Blyg