Rajini. Mudhasani, et.al., Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells., The Journal of cell biology, 2008, 181

http://rdf.ncbi.nlm.nih.gov/pubmed/18591425

Rajini. Mudhasani, et.al., Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells., The Journal of cell biology, 2008, 181

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dicer1<tm1Snj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809260
• Dicer1<tm1.1Snj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809262

class

http://purl.org/net/cito/citesAsAuthority

• Dicer1<tm1Snj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809260
• Dicer1<tm1.1Snj>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809262

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal epidermal layer morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001216I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• decreased embryo size_Dicer1<tm1.1Snj>/Dicer1<tm1.1Snj>
  http://metadb.riken.jp/0001698I129S7SvEvBrdC57BL6Dicer1tm11SnjDicer1tm11SnjDicer1tm11Snj
• decreased cell proliferation_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0000352I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• abnormal cell physiology_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0005621I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• abnormal mitosis_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0004046I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• increased cell proliferation_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0000351I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjTrp53tm1BrdTrp53tm1BrdDicer1tm1SnjTrp53tm1Brd
• no abnormal phenotype detected_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0002169I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• early cellular replicative senescence_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0008008I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• abnormal DNA replication_Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0008057I129S7SvEvBrdC57BL6Dicer1tm1SnjDicer1tm1SnjDicer1tm1Snj
• alopecia_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0000414I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• abnormal limb development_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0006279I129S7SvEvBrdC57BL6CBADicer1tm1SnjDicer1tm1SnjTgCAGcreEsr15Amc0Dicer1tm1SnjTgCAGcreEsr15Amc
• increased cell proliferation_Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Dicer1<tm1Snj>/Dicer1<tm1Snj>
  http://metadb.riken.jp/0000351I129Sv129S7SvEvBrdC57BL6SJLCdkn2atm1RdpCdkn2atm1RdpDicer1tm1SnjDicer1tm1SnjDicer1tm1SnjCdkn2atm1Rdp