Hua-Qin. Wang, et.al., Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss., Journal of neurochemistry, 2008, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/18691389

Hua-Qin. Wang, et.al., Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss., Journal of neurochemistry, 2008, 107

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• oxidative stress_Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0003674IC3HC57BL6TgPrpGPR371Ryot0TgPrpGPR371Ryot
• neuron degeneration_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0003224I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• decreased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0005643I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• loss of dopaminergic neurons_Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0003244IC3HC57BL6TgPrpGPR371Ryot0TgPrpGPR371Ryot
• neuron degeneration_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(PDGFB-GPR37)20Ryot/Tg(PDGFB-GPR37)20Ryot
  http://metadb.riken.jp/0003224I129P2OlaHsdC57BL6Park2tm1YktPark2tm1YktTgPDGFBGPR3720RyotTgPDGFBGPR3720RyotPark2tm1YktTgPDGFBGPR3720Ryot
• decreased dopaminergic neuron number_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
  http://metadb.riken.jp/0011448I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371RyotTgPrpGPR371RyotPark2tm1YktTgPrpGPR371Ryot
• increased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
  http://metadb.riken.jp/0001906I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371RyotTgPrpGPR371RyotPark2tm1YktTgPrpGPR371Ryot
• decreased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
  http://metadb.riken.jp/0005643I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371RyotTgPrpGPR371RyotPark2tm1YktTgPrpGPR371Ryot
• oxidative stress_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0003674I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• decreased dopaminergic neuron number_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0011448I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• abnormal redox activity_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0003186I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• neuron degeneration_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(PDGFB-GPR37)20Ryot/0
  http://metadb.riken.jp/0003224I129P2OlaHsdC57BL6Park2tm1YktPark2tm1YktTgPDGFBGPR3720Ryot0Park2tm1YktTgPDGFBGPR3720Ryot
• increased dopamine level_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/0
  http://metadb.riken.jp/0001906I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371Ryot0Park2tm1YktTgPrpGPR371Ryot
• abnormal redox activity_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
  http://metadb.riken.jp/0003186I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371RyotTgPrpGPR371RyotPark2tm1YktTgPrpGPR371Ryot
• neuron degeneration_Park2<tm1Ykt>/Park2<tm1Ykt>,Tg(Prp-GPR37)1Ryot/Tg(Prp-GPR37)1Ryot
  http://metadb.riken.jp/0003224I129P2OlaHsdC3HC57BL6Park2tm1YktPark2tm1YktTgPrpGPR371RyotTgPrpGPR371RyotPark2tm1YktTgPrpGPR371Ryot