Z. Michailidou, et.al., Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/18697839

Z. Michailidou, et.al., Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<Gt(ESKN92)Hgs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3817754

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating corticosterone level_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0001745B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• increased systemic arterial systolic blood pressure_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0006144B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• postnatal lethality, complete penetrance_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<Gt(ESKN92)Hgs>
  http://metadb.riken.jp/0011085B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1GtESKN92Hgs
• increased liver triglyceride level_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0009355B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• increased circulating angiotensinogen level_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0006375B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• increased renin activity_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0005582B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• enlarged adrenal glands_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0000642B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• abnormal adrenal gland zona fasciculata morphology_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0008294B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• abnormal adrenal gland morphology_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0000639B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• abnormal adrenal gland zona glomerulosa morphology_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0008293B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• abnormal circulating corticosterone level_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0005345B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs
• increased circulating aldosterone level_Nr3c1<Gt(ESKN92)Hgs>/Nr3c1<+>
  http://metadb.riken.jp/0002666B6CgNr3c1GtESKN92HgsNr3c1GtESKN92HgsNr3c1Nr3c1Nr3c1GtESKN92Hgs

class

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<Gt(ESKN92)Hgs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3817754