Stefan H. Gerber, et.al., Conformational switch of syntaxin-1 controls synaptic vesicle fusion., Science (New York, N.Y.), 2008, 321

http://rdf.ncbi.nlm.nih.gov/pubmed/18703708

Stefan H. Gerber, et.al., Conformational switch of syntaxin-1 controls synaptic vesicle fusion., Science (New York, N.Y.), 2008, 321

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Stx1b<tm1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765940
• Stx1a<tm2.1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809921
• Stx1b<tm1.1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3804480

class

http://purl.org/net/cito/citesAsAuthority

• Stx1b<tm1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765940
• Stx1a<tm2.1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809921
• Stx1b<tm1.1Sud>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3804480

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal excitatory postsynaptic currents_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0002910I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• absent gastric milk in neonates_Unc13a<tm1Bros>/Unc13a<tm1Bros>
  http://metadb.riken.jp/0009546NSUnc13atm1BrosUnc13atm1BrosUnc13atm1Bros
• abnormal synaptic vesicle recycling_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0004770I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• premature death_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• abnormal adrenal chromaffin cell morphology_Vamp2<tm1Sud>/Vamp2<tm1Sud>
  http://metadb.riken.jp/0008504I129P2OlaHsdVamp2tm1SudVamp2tm1SudVamp2tm1Sud
• postnatal lethality, complete penetrance_Unc13a<tm1Bros>/Unc13a<tm1Bros>
  http://metadb.riken.jp/0011085NSUnc13atm1BrosUnc13atm1BrosUnc13atm1Bros
• seizures_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0002064I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• postnatal lethality_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>,Unc13a<tm1Bros>/Unc13a<tm1Bros>
  http://metadb.riken.jp/0002082I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudUnc13atm1BrosUnc13atm1BrosUnc13atm1BrosStx1btm11Sud
• abnormal adrenal chromaffin cell morphology_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0008504I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• abnormal neuron physiology_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0004811I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• abnormal neuron morphology_Stx1a<tm2.1Sud>/Stx1a<tm2.1Sud>,Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0002882I129S1Sv129X1SvJC57BL6Stx1atm21SudStx1atm21SudStx1btm11SudStx1btm11SudStx1btm11SudStx1atm21Sud
• abnormal synaptic vesicle recycling_Stx1a<tm2.1Sud>/Stx1a<tm2.1Sud>,Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0004770I129S1Sv129X1SvJC57BL6Stx1atm21SudStx1atm21SudStx1btm11SudStx1btm11SudStx1btm11SudStx1atm21Sud
• abnormal miniature excitatory postsynaptic currents_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0004753I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• abnormal CNS synaptic transmission_Unc13a<tm1Bros>/Unc13a<tm1Bros>
  http://metadb.riken.jp/0002206NSUnc13atm1BrosUnc13atm1BrosUnc13atm1Bros
• abnormal CNS synaptic transmission_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0002206I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud
• ataxia_Stx1b<tm1.1Sud>/Stx1b<tm1.1Sud>
  http://metadb.riken.jp/0001393I129S1Sv129X1SvJC57BL6Stx1btm11SudStx1btm11SudStx1btm11Sud

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD40562
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40562