Milena. Traykova-Brauch, et.al., An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice., Nature medicine, 2008, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/18724376

Milena. Traykova-Brauch, et.al., An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice., Nature medicine, 2008, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax8-rtTA2S*M2)1Koes
  http://metadb.riken.jp/db/mgi_rdf/MGI:3709326

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Pax8-rtTA2S*M2)1Koes
  http://metadb.riken.jp/db/mgi_rdf/MGI:3709326

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• kidney epithelium hyperplasia_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-cre)LC1Bjd/0
  http://metadb.riken.jp/0004968I129S4SvJaeBALBcC57BL6DBATsc1tm1DjkTsc1tm1DjkTgPax8rtTA2SM21Koes0TgtetOcreLC1Bjd0TgPax8rtTA2SM21KoesTgtetOcreLC1BjdTsc1tm1Djk
• postnatal lethality, complete penetrance_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-cre)LC1Bjd/0
  http://metadb.riken.jp/0011085I129S4SvJaeBALBcC57BL6DBATsc1tm1DjkTsc1tm1DjkTgPax8rtTA2SM21Koes0TgtetOcreLC1Bjd0TgPax8rtTA2SM21KoesTgtetOcreLC1BjdTsc1tm1Djk
• increased renal carcinoma incidence_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-MYC)36aBop/0
  http://metadb.riken.jp/0010384IC57BL6DBAFVBNTgPax8rtTA2SM21Koes0TgtetOMYC36aBop0TgtetOMYC36aBopTgPax8rtTA2SM21Koes
• kidney failure_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-MYC)36aBop/0
  http://metadb.riken.jp/0003606IC57BL6DBAFVBNTgPax8rtTA2SM21Koes0TgtetOMYC36aBop0TgtetOMYC36aBopTgPax8rtTA2SM21Koes
• polycystic kidney_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-cre)LC1Bjd/0
  http://metadb.riken.jp/0008528I129S4SvJaeBALBcC57BL6DBATsc1tm1DjkTsc1tm1DjkTgPax8rtTA2SM21Koes0TgtetOcreLC1Bjd0TgPax8rtTA2SM21KoesTgtetOcreLC1BjdTsc1tm1Djk
• increased adenoma incidence_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-MYC)36aBop/0
  http://metadb.riken.jp/0010383IC57BL6DBAFVBNTgPax8rtTA2SM21Koes0TgtetOMYC36aBop0TgtetOMYC36aBopTgPax8rtTA2SM21Koes
• kidney cysts_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-MYC)36aBop/0
  http://metadb.riken.jp/0003675IC57BL6DBAFVBNTgPax8rtTA2SM21Koes0TgtetOMYC36aBop0TgtetOMYC36aBopTgPax8rtTA2SM21Koes
• polycystic kidney_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-MYC)36aBop/0
  http://metadb.riken.jp/0008528IC57BL6DBAFVBNTgPax8rtTA2SM21Koes0TgtetOMYC36aBop0TgtetOMYC36aBopTgPax8rtTA2SM21Koes
• renal fibrosis_Tg(Pax8-rtTA2S*M2)1Koes/0,Tg(tetO-TGFB1*C223S*C225S)1Glk/0
  http://metadb.riken.jp/0003985IC57BL6DBATgPax8rtTA2SM21Koes0TgtetOTGFB1C223SC225S1Glk0TgPax8rtTA2SM21KoesTgtetOTGFB1C223SC225S1Glk