Cristiane H. Squarize, et.al., Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin., Cancer research, 2008, 68

http://rdf.ncbi.nlm.nih.gov/pubmed/18757421

Cristiane H. Squarize, et.al., Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin., Cancer research, 2008, 68

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hair follicle morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0000377I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• skin lesions_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001212I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• abnormal hair shaft morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0003809I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• flaky skin_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001195I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• premature death_Pten<tm1Hwu>/Pten<+>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6JSJLJPtentm1HwuPtenTgKRT14creSmr0TgKRT14creSmrPtentm1HwuPten
• increased thyroid tumor incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0010316I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• enlarged thyroid gland_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0005355I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• decreased survivor rate_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0008770I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• abnormal nipple morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0006078I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• increased mammary gland tumor incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0010299I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• premature death_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• increased mammary adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001883I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• postnatal lethality, incomplete penetrance_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0011086I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• acanthosis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001874I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• increased mammary gland tumor incidence_Pten<tm1Hwu>/Pten<+>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0010299I129S4SvJaeC57BL6JSJLJPtentm1HwuPtenTgKRT14creSmr0TgKRT14creSmrPtentm1HwuPten
• abnormal vibrissa follicle morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0010234I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• increased skin papilloma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0002051I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• hyperkeratosis_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001242I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• wrinkled skin_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001211I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu
• increased mammary adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0001883I129S4SvJaeC57BL6JSJLJPtentm1HwuPtenTgKRT14creSmr0TgKRT14creSmrPtentm1HwuPten
• increased skin tumor incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(KRT14-cre)#Smr/0
  http://metadb.riken.jp/0010300I129S4SvJaeC57BL6JSJLJPtentm1HwuPtentm1HwuTgKRT14creSmr0TgKRT14creSmrPtentm1Hwu