Alexander. Seiler, et.al., Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death., Cell metabolism, 2008, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/18762024

Alexander. Seiler, et.al., Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death., Cell metabolism, 2008, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm2.1Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810784
• Gpx4<tm2Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810783

class

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm2.1Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810784
• Gpx4<tm2Marc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3810783

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• convulsive seizures_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0000947I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• ataxia_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0001393I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• embryonic lethality between implantation and somite formation, complete penetrance_Gpx4<tm2.1Marc>/Gpx4<tm2.1Marc>
  http://metadb.riken.jp/0011096I129S2SvPasBALBcC57BL6Gpx4tm21MarcGpx4tm21MarcGpx4tm21Marc
• abnormal hippocampus CA3 region morphology_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0008267I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• increased neuron apoptosis_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0003203I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• postnatal lethality_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0002082I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• weight loss_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0001263I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• abnormal somatosensory cortex morphology_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0000859I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• abnormal social/conspecific interaction_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0002557I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc
• astrocytosis_Gpx4<tm2Marc>/Gpx4<tm2Marc>,Tg(Camk2a-cre)2Gsc/0
  http://metadb.riken.jp/0003354I129S2SvPasFVBNGpx4tm2MarcGpx4tm2MarcTgCamk2acre2Gsc0Gpx4tm2MarcTgCamk2acre2Gsc

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD18148
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD18148
• CD12224
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12224
• CD41706
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41706
• CD04477
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04477