Brendan. Jones, et.al., The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure., PLoS genetics, 2008, 4

http://rdf.ncbi.nlm.nih.gov/pubmed/18787701

Brendan. Jones, et.al., The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure., PLoS genetics, 2008, 4

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dot1l<tm1Tche>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459467
• Dot1l<tm1.1Tche>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459468

class

http://purl.org/net/cito/citesAsAuthority

• Dot1l<tm1Tche>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459467
• Dot1l<tm1.1Tche>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459468

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal vitelline vasculature morphology_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0003229EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• abnormal telomere length_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0003155EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• short tail_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0000592EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• abnormal cell physiology_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0005621EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• embryonic lethality during organogenesis, complete penetrance_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0011098EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• decreased embryo size_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0001698EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• embryonic growth retardation_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0003984EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• enlarged heart_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0000274EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• decreased cell proliferation_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0000352EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• aneuploidy_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0004024EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche
• increased embryonic tissue cell apoptosis_Dot1l<tm1.1Tche>/Dot1l<tm1.1Tche>
  http://metadb.riken.jp/0013504EIC57BL6orI129SvC57BL6Dot1ltm11TcheDot1ltm11TcheDot1ltm11Tche