Lin-Yu. Lu, et.al., Polo-like kinase 1 is essential for early embryonic development and tumor suppression., Molecular and cellular biology, 2008, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/18794363

Lin-Yu. Lu, et.al., Polo-like kinase 1 is essential for early embryonic development and tumor suppression., Molecular and cellular biology, 2008, 28

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3822515

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality before implantation, complete penetrance_Plk1<Gt(RRR358)Byg>/Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/0011094I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1GtRRR358BygPlk1GtRRR358Byg
• increased sarcoma incidence_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0002032I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg
• increased lymphoma incidence_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0012431I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg
• aneuploidy_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0004024I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg
• embryonic growth arrest_Plk1<Gt(RRR358)Byg>/Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/0001730I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1GtRRR358BygPlk1GtRRR358Byg
• increased squamous cell carcinoma incidence_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0004207I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg
• abnormal cell cycle_Plk1<Gt(RRR358)Byg>/Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/0003077I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1GtRRR358BygPlk1GtRRR358Byg
• abnormal mitotic spindle morphology_Plk1<Gt(RRR358)Byg>/Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/0009760I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1GtRRR358BygPlk1GtRRR358Byg
• increased tumor incidence_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0002020I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg
• increased lung carcinoma incidence_Plk1<Gt(RRR358)Byg>/Plk1<+>
  http://metadb.riken.jp/0008714I129P2OlaHsdC57BL6Plk1GtRRR358BygPlk1Plk1Plk1GtRRR358Byg

class

http://purl.org/net/cito/citesAsAuthority

• Plk1<Gt(RRR358)Byg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3822515