Ben A. Croker, et.al., Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/18806225

Ben A. Croker, et.al., Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ptpn6<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717648

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgM level_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0002494C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• increased erythroid progenitor cell number_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0003135C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• enlarged spleen_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0000691C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• ulcerated paws_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>,Stat1<m1Btlr>/Stat1<m1Btlr>
  http://metadb.riken.jp/0000578C57BL6Stat1m1BtlrPtpn6m1BtlrPtpn6m1BtlrPtpn6m1BtlrStat1m1BtlrStat1m1BtlrPtpn6m1BtlrStat1m1Btlr
• ulcerated paws_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>,Ticam1<Lps2>/Ticam1<Lps2>
  http://metadb.riken.jp/0000578C57BL6JPtpn6m1BtlrTicam1Lps2Ptpn6m1BtlrPtpn6m1BtlrTicam1Lps2Ticam1Lps2Ticam1Lps2Ptpn6m1Btlr
• lung inflammation_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0001861C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• increased anti-chromatin antibody level_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0004829C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• decreased susceptibility to bacterial infection induced morbidity/mortality_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0009789C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• salivary gland inflammation_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0001870C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• abnormal myeloid leukocyte morphology_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0008250C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• decreased mature B cell number_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0008211C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• decreased susceptibility to bacterial infection_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0002411C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• ulcerated paws_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0000578C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr
• increased neutrophil cell number_Ptpn6<m1Btlr>/Ptpn6<m1Btlr>
  http://metadb.riken.jp/0000219C57BL6JPtpn6m1BtlrMmucdPtpn6m1BtlrPtpn6m1BtlrPtpn6m1Btlr

class

http://purl.org/net/cito/citesAsAuthority

• Ptpn6<m1Btlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717648