Ute. Koch, et.al., Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment., The Journal of experimental medicine, 2008, 205

http://rdf.ncbi.nlm.nih.gov/pubmed/18824585

Ute. Koch, et.al., Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment., The Journal of experimental medicine, 2008, 205

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dll4<tm1Frad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3828266

class

http://purl.org/net/cito/citesAsAuthority

• Dll4<tm1Frad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3828266

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased immature B cell number_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008214I129C57BL6CBANotch1tm1AgtNotch1tm1AgtTgMx1cre1Cgn0TgMx1cre1CgnNotch1tm1Agt
• decreased CD8-positive, alpha-beta T cell number_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0008079B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• abnormal thymus cell ratio_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0008827B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• abnormal T cell differentiation_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0002145B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• abnormal thymus cell ratio_Notch1<tm1Agt>/Notch1<tm1Agt>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008827I129C57BL6CBANotch1tm1AgtNotch1tm1AgtTgMx1cre1Cgn0TgMx1cre1CgnNotch1tm1Agt
• decreased thymocyte number_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0000715B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• increased immature B cell number_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0008214B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• decreased double-positive T cell number_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0005092B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1
• decreased CD4-positive, alpha beta T cell number_Dll4<tm1Frad>/Dll4<tm1Frad>,Foxn1<tm3(cre)Nrm>/Foxn1<+>
  http://metadb.riken.jp/0008075B6CgDll4tm1FradFoxn1tm3creNrmDll4tm1FradDll4tm1FradFoxn1tm3creNrmFoxn1Foxn1tm3creNrmDll4tm1FradFoxn1