Eon Joo. Park, et.al., An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart., Development (Cambridge, England), 2008, 135

http://rdf.ncbi.nlm.nih.gov/pubmed/18832392

Eon Joo. Park, et.al., An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart., Development (Cambridge, England), 2008, 135

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829030
• Fgfr1<tm1Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829029

class

http://purl.org/net/cito/citesAsAuthority

• Fgfr2<tm1Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829030
• Fgfr1<tm1Moon>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829029

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal heart development_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0000267NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• abnormal vascular development_Fgfr1<tm3.2Cxd>/Fgfr1<tm3.2Cxd>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>,Foxa2<tm2.1(cre/Esr1*)Moon>/Foxa2<+>
  http://metadb.riken.jp/0000259I129S6SvEvTac129X1SvJFgfr1tm32CxdFgfr1tm32CxdFgfr2tm1DorFgfr2tm1DorFoxa2tm21creEsr1MoonFoxa2Fgfr1tm32CxdFgfr2tm1DorFoxa2Foxa2tm21creEsr1Moon
• abnormal cardiac epithelial to mesenchymal transition_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0008825NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• bicuspid aortic valve_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0010484NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• abnormal cardiac epithelial to mesenchymal transition_Fgf8<tm1Mrc>/Fgf8<tm2Moon>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0008825I129SSvBlackSwissC57BL6Fgf8tm1MrcFgf8tm2MoonIsl1tm1creSevIsl1Fgf8tm1MrcIsl1tm1creSevFgf8tm2MoonIsl1
• abnormal cardiac outflow tract development_Fgf8<tm1Mrc>/Fgf8<tm2Moon>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006126I129SSvBlackSwissC57BL6Fgf8tm1MrcFgf8tm2MoonIsl1tm1creSevIsl1Fgf8tm1MrcIsl1tm1creSevFgf8tm2MoonIsl1
• abnormal heart morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0000266NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• abnormal conotruncal ridge morphology_Fgf8<tm1Mrc>/Fgf8<tm2Moon>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0010585I129SSvBlackSwissC57BL6Fgf8tm1MrcFgf8tm2MoonIsl1tm1creSevIsl1Fgf8tm1MrcIsl1tm1creSevFgf8tm2MoonIsl1
• abnormal cardiac outflow tract development_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0006126NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• short snout_Pax3<tm1(cre)Joe>/Pax3<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0000445NSPax3tm1creJoePax3TgCAGBgeoSpry2ALPP1Mrt0TgCAGBgeoSpry2ALPP1MrtPax3Pax3tm1creJoe
• persistent truncus arteriosis_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0002633NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• double outlet right ventricle_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0000284NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• facial cleft_Fgfr1<tm1Jpa>/Fgfr1<tm1Jpa>,Fgfr2<tm1Dor>/Fgfr2<tm1Dor>
  http://metadb.riken.jp/0008797I129S1Sv129X1SvJC57BL6JCBAJFgfr1tm1JpaFgfr1tm1JpaFgfr2tm1DorFgfr2tm1DorFgfr2tm1DorFgfr1tm1Jpa
• short mandible_Pax3<tm1(cre)Joe>/Pax3<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0000088NSPax3tm1creJoePax3TgCAGBgeoSpry2ALPP1Mrt0TgCAGBgeoSpry2ALPP1MrtPax3Pax3tm1creJoe
• atrioventricular septal defect_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0010412NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1
• persistent truncus arteriosis_Fgf8<tm1Mrc>/Fgf8<tm2Moon>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0002633I129SSvBlackSwissC57BL6Fgf8tm1MrcFgf8tm2MoonIsl1tm1creSevIsl1Fgf8tm1MrcIsl1tm1creSevFgf8tm2MoonIsl1
• ventricular septal defect_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0
  http://metadb.riken.jp/0010402NSMesp1tm2creYsaMesp1TgCAGBgeoSpry2ALPP1Mrt0Mesp1tm2creYsaTgCAGBgeoSpry2ALPP1MrtMesp1

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD10349
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10349
• CD04767
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04767