Lars M. Ittner, et.al., Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

http://rdf.ncbi.nlm.nih.gov/pubmed/18832465

Lars M. Ittner, et.al., Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-MAPT*K369I)K3Gotz
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833383

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal gait_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001406B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• muscular atrophy_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0002269B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• abnormal axon morphology_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0005404B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• short stride length_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001407B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• bradykinesia_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0005156B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• abnormal neuron morphology_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0002882B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• impaired coordination_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001405B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• abnormal motor capabilities/coordination/movement_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0002066B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• loss of dopaminergic neurons_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0003244B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• decreased body weight_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001262B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• abnormal object recognition memory_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001458B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• decreased dopamine level_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0005643B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• abnormal axonal transport_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0004768B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• limb grasping_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0001513B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• tremors_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0000745B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz
• enhanced behavioral response to xenobiotic_Tg(Thy1-MAPT*K369I)K3Gotz/0
  http://metadb.riken.jp/0009746B6CgTgThy1MAPTK369IK3GotzTgThy1MAPTK369IK3Gotz0TgThy1MAPTK369IK3Gotz

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Thy1-MAPT*K369I)K3Gotz
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833383