Kajsa. Wing, et.al., CTLA-4 control over Foxp3+ regulatory T cell function., Science (New York, N.Y.), 2008, 322

http://rdf.ncbi.nlm.nih.gov/pubmed/18845758

Kajsa. Wing, et.al., CTLA-4 control over Foxp3+ regulatory T cell function., Science (New York, N.Y.), 2008, 322

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctla4<tm1Saka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3812204
• Foxp3<tm1(cre)Saka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3812203

class

http://purl.org/net/cito/citesAsAuthority

• Ctla4<tm1Saka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3812204
• Foxp3<tm1(cre)Saka>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3812203

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased regulatory T cell number_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0004973IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• lung inflammation_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001861IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased autoantibody level_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0003725IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• abnormal splenic cell ratio_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0008826IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• abnormal liver morphology_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0000598IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• premature death_Ctla4<tm1Mak>/Ctla4<tm1Mak>
  http://metadb.riken.jp/0002083I129P2OlaHsdBALBcCtla4tm1MakCtla4tm1MakCtla4tm1Mak
• increased interferon-gamma secretion_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0008566IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased autoantibody level_Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0003725IBALBcFoxp3tm1creSakaYFoxp3tm1creSaka
• increased interleukin-2 secretion_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0008687IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• premature death_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0002083IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• lymph node hyperplasia_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0008102IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• abnormal regulatory T cell physiology_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0004946IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• salivary gland inflammation_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001870IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• stomach inflammation_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001873IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased interleukin-17 secretion_Ctla4<tm1Mak>/Ctla4<tm1Mak>
  http://metadb.riken.jp/0008681I129P2OlaHsdBALBcCtla4tm1MakCtla4tm1MakCtla4tm1Mak
• increased interferon-gamma secretion_Ctla4<tm1Mak>/Ctla4<tm1Mak>
  http://metadb.riken.jp/0008566I129P2OlaHsdBALBcCtla4tm1MakCtla4tm1MakCtla4tm1Mak
• increased IgE level_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0002497IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased interleukin-2 secretion_Ctla4<tm1Mak>/Ctla4<tm1Mak>
  http://metadb.riken.jp/0008687I129P2OlaHsdBALBcCtla4tm1MakCtla4tm1MakCtla4tm1Mak
• spleen hyperplasia_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0000693IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• myocarditis_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001856IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• abnormal immunoglobulin level_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0002490IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased inflammatory response_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001846IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• stomach inflammation_Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0001873IBALBcFoxp3tm1creSakaYFoxp3tm1creSaka
• increased interleukin-4 secretion_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0008699IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• enlarged heart_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0000274IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka
• increased interleukin-4 secretion_Ctla4<tm1Mak>/Ctla4<tm1Mak>
  http://metadb.riken.jp/0008699I129P2OlaHsdBALBcCtla4tm1MakCtla4tm1MakCtla4tm1Mak
• increased IgG level_Ctla4<tm1Saka>/Ctla4<tm1Saka>,Foxp3<tm1(cre)Saka>/Y
  http://metadb.riken.jp/0002493IBALBcCtla4tm1SakaCtla4tm1SakaFoxp3tm1creSakaYCtla4tm1SakaFoxp3tm1creSaka