Helen. Heath, et.al., CTCF regulates cell cycle progression of alphabeta T cells in the thymus., The EMBO journal, 2008, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/18923423

Helen. Heath, et.al., CTCF regulates cell cycle progression of alphabeta T cells in the thymus., The EMBO journal, 2008, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctcf<tm1.1Laat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829010

class

http://purl.org/net/cito/citesAsAuthority

• Ctcf<tm1.1Laat>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829010

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• postnatal lethality, incomplete penetrance_Ctcf<tm1.1Laat>/Ctcf<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Ctcftm11LaatCtcfCtcfCtcftm11Laat
• decreased CD4-positive, alpha beta T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• thymus hypoplasia_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0001823I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• decreased double-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6C57BL10DBA2JCtcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTgLckcre1CwiCtcftm1Laat
• increased single-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008082I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• decreased CD4-positive, alpha beta T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6C57BL10DBA2JCtcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTgLckcre1CwiCtcftm1Laat
• decreased double-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• increased double-negative T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• embryonic lethality during organogenesis, complete penetrance_Ctcf<tm1.1Laat>/Ctcf<tm1.1Laat>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6Ctcftm11LaatCtcftm11LaatCtcftm11Laat
• decreased CD8-positive, alpha-beta T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• decreased single-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008083I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• abnormal T cell differentiation_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• increased double-negative T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• decreased CD8-positive, alpha-beta T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6C57BL10DBA2JCtcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTgLckcre1CwiCtcftm1Laat
• decreased CD4-positive, alpha beta T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat
• decreased double-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• decreased double-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Rag2<tm1Fwa>/Rag2<tm1Fwa>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005092I129P2OlaHsd129SSvEvC57BL6C57BL10Ctcftm1LaatCtcftm1LaatRag2tm1FwaRag2tm1FwaTgLckcre1Cwi0Ctcftm1LaatTgLckcre1CwiRag2tm1Fwa
• decreased T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0005018I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• decreased CD4-positive, alpha beta T cell number_Ctcf<tm1Laat>/Ctcf<+>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6Ctcftm1LaatCtcfTgLckcre1Cwi0Ctcftm1LaatTgLckcre1CwiCtcf
• thymus hypoplasia_Ctcf<tm1Laat>/Ctcf<+>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0001823I129P2OlaHsdC57BL6Ctcftm1LaatCtcfTgLckcre1Cwi0Ctcftm1LaatTgLckcre1CwiCtcf
• abnormal T cell differentiation_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraH-Y,TcrbH-Y)71Vbo/0
  http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6C57BL10DBA2JCtcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraHYTcrbHY71Vbo0TgTcraHYTcrbHY71VboTgLckcre1CwiCtcftm1Laat
• decreased CD8-positive, alpha-beta T cell number_Ctcf<tm1Laat>/Ctcf<+>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6Ctcftm1LaatCtcfTgLckcre1Cwi0Ctcftm1LaatTgLckcre1CwiCtcf
• abnormal T cell differentiation_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• increased single-positive T cell number_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0,Tg(TcraTcrb)425Cbn/0
  http://metadb.riken.jp/0008082I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgTcraTcrb425Cbn0TgLckcre1CwiCtcftm1LaatTgTcraTcrb425Cbn
• abnormal T cell morphology_Ctcf<tm1Laat>/Ctcf<tm1Laat>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008037I129P2OlaHsdC57BL6Ctcftm1LaatCtcftm1LaatTgLckcre1Cwi0TgLckcre1CwiCtcftm1Laat