Eric S. Mullins, et.al., Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain., Blood, 2009, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/18927430

Eric S. Mullins, et.al., Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain., Blood, 2009, 113

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• F2<tm1Jld>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831686

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• increased susceptibility to bacterial infection_F2<tm1Jld>/F2<tm1Jld>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002412B6CgF2tm1JldTgMx1cre1CgnF2tm1JldF2tm1JldTgMx1cre1Cgn0F2tm1JldTgMx1cre1Cgn
• increased bleeding time_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005606I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• no abnormal phenotype detected_F2<tm1Jld>/F2<tm1Jld>
  http://metadb.riken.jp/0002169B6129P2F2tm1JldF2tm1JldF2tm1JldF2tm1Jld
• hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001914I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• spinal hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0006054I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• petechiae_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008816I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• abnormal heart morphology_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000266I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• abnormal blood coagulation_F2<tm1Jld>/F2<tm1Sjd>
  http://metadb.riken.jp/0002551I129P2OlaHsdC57BL6JF2tm1JldF2tm1SjdF2tm1JldF2tm1Sjd
• abnormal blood coagulation_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0002551I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• cardiac fibrosis_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003141I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• gastrointestinal hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000465I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• heart hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0009698I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• skin hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0011514I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• increased bleeding time_F2<tm1Jld>/F2<tm1Sjd>
  http://metadb.riken.jp/0005606I129P2OlaHsdC57BL6JF2tm1JldF2tm1SjdF2tm1JldF2tm1Sjd
• intracranial hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001915I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• genital hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004245I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• cerebellum hemorrhage_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0006052I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld
• hemothorax_F2<tm1Jld>/F2<tm1Sjd>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0005243I129P2OlaHsdC57BL6C57BL6JCBAF2tm1JldF2tm1SjdTgMx1cre1Cgn0F2tm1SjdTgMx1cre1CgnF2tm1Jld

class

http://purl.org/net/cito/citesAsAuthority

• F2<tm1Jld>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831686