Ullas. Kolthur-Seetharam, et.al., The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling., Biology of reproduction, 2009, 80

http://rdf.ncbi.nlm.nih.gov/pubmed/18987333

Ullas. Kolthur-Seetharam, et.al., The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling., Biology of reproduction, 2009, 80

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal Sertoli cell development_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0004109129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• arrest of spermatogenesis_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0001155129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• male infertility_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0001925129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• arrest of male meiosis_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0008261129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• premature death_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0002083129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• decreased circulating follicle stimulating hormone level_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0002790129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal male germ cell apoptosis_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0008280129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal spermatid morphology_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0006380129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• decreased body size_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0001265129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal spermatocyte morphology_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0006379129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• postnatal growth retardation_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0001732129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• small seminiferous tubules_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0001153129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal adult Leydig cell differentiation_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0013604129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal seminiferous tubule morphology_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0002216129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• Leydig cell hypoplasia_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0005536129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• decreased circulating luteinizing hormone level_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0002773129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby
• abnormal testes secretion_Sirt1<tm1Mcby>/Sirt1<tm1Mcby>
  http://metadb.riken.jp/0002782129SvSirt1tm1McbySirt1tm1McbySirt1tm1McbySirt1tm1Mcby

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal Leydig cell morphology in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014562
• abnormal male germ cell apoptosis in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010772
• decreased circulating luteinizing hormone level in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008064
• abnormal spermatocyte morphology in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008082
• Leydig cell hypoplasia in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008079
• abnormal testes secretion in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008065
• abnormal Sertoli cell development in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008070
• abnormal adult Leydig cell differentiation in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008095
• small seminiferous tubules in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008042
• arrest of spermatogenesis in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008043
• decreased circulating follicle stimulating hormone level in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008066
• postnatal growth retardation in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008050
• arrest of male meiosis in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008084
• abnormal seminiferous tubule morphology in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008058
• premature death in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1008056
• abnormal spermatid morphology in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010771
• reproductive system phenotype in RBRC05323
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1015679