Linda J. Mullins, et.al., Cyp11b1 null mouse, a model of congenital adrenal hyperplasia., The Journal of biological chemistry, 2009, 284

http://rdf.ncbi.nlm.nih.gov/pubmed/19029289

Linda J. Mullins, et.al., Cyp11b1 null mouse, a model of congenital adrenal hyperplasia., The Journal of biological chemistry, 2009, 284

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3841929

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hypokalemia_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0004119I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• absent corpus luteum_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0001134I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased total body fat amount_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0010025I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• enlarged uterus_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0004906I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased urine corticosterone level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0011550I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased brain weight_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0002176I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• pituitary gland hyperplasia_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0000635I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased urine progesterone level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0011546I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased circulating insulin level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0002727I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• abnormal adrenal gland zona fasciculata morphology_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0008294I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased urine deoxycorticosterone level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0011553I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• uterus cysts_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0009082I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• adrenal gland hyperplasia_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0009078I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased systemic arterial systolic blood pressure_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0006144I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased heart weight_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0002833I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• uterus adenomyosis_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0009221I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• enlarged adrenal glands_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0000642I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased circulating corticosterone level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0002665I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• impaired glucose tolerance_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0005293I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased liver weight_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0002981I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased thymus weight_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0004956I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased circulating adrenocorticotropin level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0001748I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• increased kidney weight_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0003917I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased urine aldosterone level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0011541I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• endometrium hyperplasia_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0009092I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• female infertility_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0001926I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk
• decreased circulating renin level_Cyp11b1<tm1Chjk>/Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/0003353I129P2OlaHsdC57BL6JCyp11b1tm1ChjkCyp11b1tm1ChjkCyp11b1tm1Chjk

class

http://purl.org/net/cito/citesAsAuthority

• Cyp11b1<tm1Chjk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3841929

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD44660
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44660