Toshiya. Sato, et.al., Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice., Human molecular genetics, 2009, 18

http://rdf.ncbi.nlm.nih.gov/pubmed/19039037

Toshiya. Sato, et.al., Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice., Human molecular genetics, 2009, 18

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(ATN1*)Q129Stsu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834570

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebral cortex morphology_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0000788I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal CNS synaptic transmission_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002206I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal nervous system electrophysiology_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002272I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• decreased brain size_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0000774I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal paired-pulse facilitation_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002918I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• neuronal intranuclear inclusions_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0004191I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal GABA-mediated receptor currents_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0004008I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal neuron morphology_Tg(ATN1*)Drm21Stsu/0
  http://metadb.riken.jp/0002882I129SSvEvC57BL6JTgATN1Drm21Stsu0TgATN1Drm21Stsu
• decreased blood osmolality_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0008998I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• absence seizures_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0003216I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• enhanced paired-pulse facilitation_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002919I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• abnormal excitatory postsynaptic potential_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002912I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• decreased circulating antidiuretic hormone level_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0005611I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• increased fluid intake_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0011941I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• decreased urine osmolality_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002988I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• decreased brain weight_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002175I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• ataxia_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0001393I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• jerky movement_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0005424I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• premature death_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0002083I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• polyuria_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0001762I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• decreased body weight_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0001262I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu
• reduced long term potentiation_Tg(ATN1*)Q129Stsu/0
  http://metadb.riken.jp/0001473I129SSvEvC57BL6JTgATN1Q129Stsu0TgATN1Q129Stsu

class

http://purl.org/net/cito/citesAsAuthority

• Tg(ATN1*)Q129Stsu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3834570