Pazit. Polak, et.al., Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration., Cell metabolism, 2008, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/19046571

Pazit. Polak, et.al., Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration., Cell metabolism, 2008, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rptor<tm1.1Rueg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829706

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body weight_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0001262I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased liver triglyceride level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009356I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• improved glucose tolerance_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005292I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased circulating leptin level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005668I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased brown adipose tissue amount_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0001780I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• increased lean body mass_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0003960I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased susceptibility to diet-induced obesity_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005659I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased white fat cell number_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009131I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased circulating glucose level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005560I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• hypoactivity_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0001402I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• increased oxygen consumption_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005289I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• reduced female fertility_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0001923I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased adiponectin level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0004893I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased circulating cholesterol level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0005179I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased white fat cell size_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0009133I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• embryonic lethality, complete penetrance_Rptor<tm1.1Rueg>/Rptor<tm1.1Rueg>
  http://metadb.riken.jp/0011092I129S1SvImJBALBcJC57BL6JRptortm11RuegRptortm11RuegRptortm11Rueg
• decreased total fat pad weight_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0008907I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• decreased circulating insulin level_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0002727I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg
• abnormal cell differentiation_Rptor<tm1.1Rueg>/Rptor<+>
  http://metadb.riken.jp/0005076I129S1SvImJBALBcJC57BL6JRptortm11RuegRptorRptorRptortm11Rueg
• decreased litter size_Rptor<tm1Rueg>/Rptor<tm1Rueg>,Tg(Fabp4-cre)1Rev/0
  http://metadb.riken.jp/0001935I129S1SvImJC57BL6JRptortm1RuegRptortm1RuegTgFabp4cre1Rev0TgFabp4cre1RevRptortm1Rueg

class

http://purl.org/net/cito/citesAsAuthority

• Rptor<tm1.1Rueg>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829706