Jing. Yu, et.al., A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney., Development (Cambridge, England), 2009, 136

http://rdf.ncbi.nlm.nih.gov/pubmed/19060336

Jing. Yu, et.al., A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney., Development (Cambridge, England), 2009, 136

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• truncated loop of Henle_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011345I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• abnormal kidney medulla development_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003613I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• absent kidney medulla_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011438I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• abnormal kidney morphology_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0002135I129X1SvJC57BL6Wnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0TgHoxb7cre13AmcWnt7btm21AmcWnt7btm2Amc
• postnatal lethality, complete penetrance_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0011085I129X1SvJC57BL6Wnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0TgHoxb7cre13AmcWnt7btm21AmcWnt7btm2Amc
• kidney failure_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0003606I129X1SvJC57BL6Wnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0TgHoxb7cre13AmcWnt7btm21AmcWnt7btm2Amc
• decreased urine osmolality_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0002988I129X1SvJC57BL6Wnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0TgHoxb7cre13AmcWnt7btm21AmcWnt7btm2Amc
• abnormal kidney morphology_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002135I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• absent kidney medulla_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0011438I129X1SvJC57BL6Wnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0TgHoxb7cre13AmcWnt7btm21AmcWnt7btm2Amc
• abnormal kidney collecting duct epithelium morphology_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011843I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• increased kidney apoptosis_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011368I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• abnormal kidney cell proliferation_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011439I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• decreased kidney cell proliferation_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011441I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• hydroureter_Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000536I129X1SvJC57BL6CBAWnt7btm2AmcWnt7btm21AmcTgSox2cre1Amc0TgSox2cre1AmcWnt7btm21AmcWnt7btm2Amc
• dilated kidney collecting duct_Gt(ROSA)26Sor<tm1Sor>/?,Wnt7b<tm2Amc>/Wnt7b<tm2.1Amc>,Tg(Hoxb7-cre)13Amc/0
  http://metadb.riken.jp/0004860I129S4SvJaeSor129X1SvJC57BL6GtROSA26Sortm1SorWnt7btm2AmcWnt7btm21AmcTgHoxb7cre13Amc0Wnt7btm21AmcWnt7btm2AmcGtROSA26Sortm1SorTgHoxb7cre13Amc