Jochen C. Hartner, et.al., ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling., Nature immunology, 2009, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/19060901

Jochen C. Hartner, et.al., ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling., Nature immunology, 2009, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Adar<tm1.1Phs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3828307

class

http://purl.org/net/cito/citesAsAuthority

• Adar<tm1.1Phs>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3828307

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal circulating interferon-beta level_Adar<tm2Phs>/Adar<tm2Phs>
  http://metadb.riken.jp/0008550B6CgAdartm2PhsAdartm2PhsAdartm2PhsAdartm2Phs
• liver hypoplasia_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0000600I129S1Sv129X1SvJC57BL6CBAAdartm11PhsAdartm2PhsTgMx1cre1CgnAdartm2PhsAdartm11PhsTgMx1cre1Cgn
• abnormal definitive hematopoiesis_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0002123I129S1Sv129X1SvJC57BL6CBAAdartm11PhsAdartm2PhsTgMx1cre1CgnAdartm2PhsAdartm11PhsTgMx1cre1Cgn
• increased circulating interferon-alpha level_Adar<tm2Phs>/Adar<tm2Phs>
  http://metadb.riken.jp/0008573B6CgAdartm2PhsAdartm2PhsAdartm2PhsAdartm2Phs
• abnormal hematopoietic stem cell morphology_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Tal1-cre/ERT)42-056Jrg/?
  http://metadb.riken.jp/0004808I129S1Sv129X1SvJC57BL6Adartm11PhsAdartm2PhsTgTal1creERT42056JrgAdartm11PhsTgTal1creERT42056JrgAdartm2Phs
• decreased bone marrow cell number_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Tal1-cre/ERT)42-056Jrg/?
  http://metadb.riken.jp/0000333I129S1Sv129X1SvJC57BL6Adartm11PhsAdartm2PhsTgTal1creERT42056JrgAdartm11PhsTgTal1creERT42056JrgAdartm2Phs
• abnormal hematopoietic stem cell morphology_Adar<tm2Phs>/Adar<tm2Phs>
  http://metadb.riken.jp/0004808B6CgAdartm2PhsAdartm2PhsAdartm2PhsAdartm2Phs
• postnatal lethality, complete penetrance_Adar<tm1.1Phs>/Adar<tm2Phs>,Tg(Mx1-cre)1Cgn/?
  http://metadb.riken.jp/0011085I129S1Sv129X1SvJC57BL6CBAAdartm11PhsAdartm2PhsTgMx1cre1CgnAdartm2PhsAdartm11PhsTgMx1cre1Cgn