P. Nagarajan, et.al., Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis., Oncogene, 2009, 28

http://rdf.ncbi.nlm.nih.gov/pubmed/19137022

P. Nagarajan, et.al., Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis., Oncogene, 2009, 28

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal kidney morphology_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0002135I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• kyphosis_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0000160I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• heart inflammation_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0001853I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• increased cellular sensitivity to X-ray irradiation_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0002879I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• increased cellular sensitivity to ultraviolet irradiation_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0008410I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• arteritis_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0010138I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• abnormal erythropoiesis_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0000245I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• abnormal DNA repair_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0008058I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• hemorrhage_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0001914I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• abnormal cell cycle_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0003077I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• increased cellular sensitivity to methylmethanesulfonate_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0008404I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• hemorrhage_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0001914I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• decreased body size_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• increased CD4-positive, alpha beta T cell number_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0008074I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• decreased birth body size_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0009703I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• increased T cell derived lymphoma incidence_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0002024I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• extramedullary hematopoiesis_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0000240I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• postnatal lethality_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0002082I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• decreased lymphocyte cell number_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0005016I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• premature death_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• abnormal blood vessel morphology_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0001614I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• abnormal blood cell morphology/development_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0002429I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• weight loss_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0001263I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• decreased survivor rate_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0008770I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• lordosis_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0000162I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• decreased erythroid progenitor cell number_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0008973I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• increased lymphoma incidence_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0012431I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• abnormal blood vessel morphology_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0001614I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• postnatal lethality, incomplete penetrance_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg
• increased megakaryocyte cell number_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0008254I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• lethargy_Chd2<Gt(RRBO46)Byg>/Chd2<Gt(RRBO46)Byg>
  http://metadb.riken.jp/0005202I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2GtRRBO46BygChd2GtRRBO46Byg
• lymphoid hyperplasia_Chd2<Gt(RRBO46)Byg>/Chd2<+>
  http://metadb.riken.jp/0000688I129P2OlaHsdC57BL6Chd2GtRRBO46BygChd2Chd2Chd2GtRRBO46Byg

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD23478
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD23478