M. Trudel, et.al., Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD., The EMBO journal, 1991, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/1915288

M. Trudel, et.al., Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD., The EMBO journal, 1991, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(LCR-HBA2,LCR-HBB*)1Cos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509327

class

http://purl.org/net/cito/citesAsAuthority

• Tg(LCR-HBA2,LCR-HBB*)1Cos
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509327

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased mean corpuscular volume_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0002591IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• abnormal gas homeostasis_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0003948IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• anemia_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0001577IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• enlarged spleen_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0000691IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• enlarged spleen_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0000691IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• increased mean corpuscular hemoglobin concentration_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0005641IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• decreased hematocrit_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0000208IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• anemia_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0001577IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• abnormal hemoglobin_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0001588IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• maternal effect_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0003718IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• postnatal lethality, incomplete penetrance_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0011086IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• pallor_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0003717IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• abnormal erythrocyte morphology_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0002447IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• increased mean corpuscular hemoglobin concentration_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0005641IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• abnormal erythrocyte morphology_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0002447IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• decreased body size_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0001265IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• decreased hematocrit_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0000208IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• increased sensitivity to induced morbidity/mortality_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0009763IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• abnormal erythrocyte physiology_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0003656IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos
• reticulocytosis_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0002640IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• maternal effect_Hbb<d3th>/Hbb<+>,Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0003718IC57BL6JCBAJDBA2JHbbd3thHbbTgLCRHBA2LCRHBB1Cos0HbbHbbd3thTgLCRHBA2LCRHBB1Cos
• postnatal lethality, incomplete penetrance_Tg(LCR-HBA2,LCR-HBB*)1Cos/0
  http://metadb.riken.jp/0011086IC57BL6JCBAJTgLCRHBA2LCRHBB1Cos0TgLCRHBA2LCRHBB1Cos