Miaofen G. Hu, et.al., A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis., Cancer research, 2009, 69

http://rdf.ncbi.nlm.nih.gov/pubmed/19155308

Miaofen G. Hu, et.al., A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis., Cancer research, 2009, 69

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdk6<tm1Phin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833563
• Cdk6<tm1.1Phin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833566

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0008079I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• thymus hypoplasia_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0001823I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• premature death_Cdk6<tm1Phin>/Cdk6<+>,Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002083I129S4SvJaeCdk6tm1PhinCdk6TgLckAkt1E40KE3Pnt0TgLckAkt1E40KE3PntCdk6Cdk6tm1Phin
• decreased thymocyte number_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0000715I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• premature death_Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002083NSTgLckAkt1E40KE3Pnt0TgLckAkt1E40KE3Pnt
• abnormal lymphopoiesis_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0002401I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• abnormal T cell differentiation_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0002145I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• decreased double-positive T cell number_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0005092I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• abnormal thymocyte activation_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0003850I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• increased T cell derived lymphoma incidence_Cdk6<tm1Phin>/Cdk6<+>,Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002024I129S4SvJaeCdk6tm1PhinCdk6TgLckAkt1E40KE3Pnt0TgLckAkt1E40KE3PntCdk6Cdk6tm1Phin
• abnormal T cell differentiation_Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002145NSTgLckAkt1E40KE3Pnt0TgLckAkt1E40KE3Pnt
• increased T cell derived lymphoma incidence_Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002024NSTgLckAkt1E40KE3Pnt0TgLckAkt1E40KE3Pnt
• thymus atrophy_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0003644I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• decreased thymocyte apoptosis_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0009542I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin
• abnormal T cell differentiation_Cdk6<tm1Phin>/Cdk6<tm1Phin>,Tg(Lck-Akt1*E40K)E-3Pnt/0
  http://metadb.riken.jp/0002145I129S4SvJaeCdk6tm1PhinCdk6tm1PhinTgLckAkt1E40KE3Pnt0Cdk6tm1PhinTgLckAkt1E40KE3Pnt
• decreased double-negative T cell number_Cdk6<tm1Phin>/Cdk6<tm1Phin>
  http://metadb.riken.jp/0005089I129S4SvJaeCdk6tm1PhinCdk6tm1PhinCdk6tm1Phin

class

http://purl.org/net/cito/citesAsAuthority

• Cdk6<tm1Phin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833563
• Cdk6<tm1.1Phin>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3833566