Anne M. Verhagen, et.al., A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency., Journal of immunology (Baltimore, Md. : 1950), 2009, 182

http://rdf.ncbi.nlm.nih.gov/pubmed/19201855

Anne M. Verhagen, et.al., A kinase-dead allele of Lyn attenuates autoimmune disease normally associated with Lyn deficiency., Journal of immunology (Baltimore, Md. : 1950), 2009, 182

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lyn<mld4>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3832561

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased erythroid progenitor cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0003135IC57BL6Lynmld4Lynmld4Lynmld4
• abnormal B cell morphology_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0004939IC57BL6Lynmld4Lynmld4Lynmld4
• abnormal B cell activation_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0008217IC57BL6Lynmld4Lynmld4Lynmld4
• increased IgE level_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0002497IC57BL6Lynmld4Lynmld4Lynmld4
• abnormal myelopoiesis_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0001601B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased neutrophil cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0000219IC57BL6Lynmld4Lynmld4Lynmld4
• decreased marginal zone B cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0008182IC57BL6Lynmld4Lynmld4Lynmld4
• decreased follicular B cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0008174IC57BL6Lynmld4Lynmld4Lynmld4
• decreased transitional stage B cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0008190IC57BL6Lynmld4Lynmld4Lynmld4
• spleen hypoplasia_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0000694IC57BL6Lynmld4Lynmld4Lynmld4
• decreased erythrocyte cell number_Lyn<mld4>/Lyn<mld4>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0002875B6129S1Mpltm1WsaLynmld4Lynmld4Mpltm1WsaMpltm1WsaLynmld4Mpltm1Wsa
• glomerulonephritis_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0002743IC57BL6Lynmld4Lynmld4Lynmld4
• increased anti-double stranded DNA antibody level_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0004762IC57BL6Lynmld4Lynmld4Lynmld4
• decreased marginal zone B cell number_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0008182B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• decreased leukocyte cell number_Lyn<mld4>/Lyn<mld4>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0000221B6129S1Mpltm1WsaLynmld4Lynmld4Mpltm1WsaMpltm1WsaLynmld4Mpltm1Wsa
• abnormal B cell morphology_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0004939B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased T cell number_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0005015B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased anti-nuclear antigen antibody level_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0004794B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased anti-double stranded DNA antibody level_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0004762B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased macrophage cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0005425IC57BL6Lynmld4Lynmld4Lynmld4
• peritoneal inflammation_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0003303IC57BL6Lynmld4Lynmld4Lynmld4
• decreased follicular B cell number_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0008174B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• spleen hypoplasia_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0000694B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• increased T cell number_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0005015IC57BL6Lynmld4Lynmld4Lynmld4
• glomerulonephritis_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0002743B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• peritoneal inflammation_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0003303B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• abnormal myelopoiesis_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0001601IC57BL6Lynmld4Lynmld4Lynmld4
• increased IgM level_Lyn<mld4>/Lyn<mld4>
  http://metadb.riken.jp/0002494IC57BL6Lynmld4Lynmld4Lynmld4
• abnormal B cell activation_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0008217B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• decreased transitional stage B cell number_Lyn<tm1Ard>/Lyn<tm1Ard>
  http://metadb.riken.jp/0008190B6129P2Lyntm1ArdLyntm1ArdLyntm1ArdLyntm1Ard
• thrombocytopenia_Lyn<mld4>/Lyn<mld4>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0003179B6129S1Mpltm1WsaLynmld4Lynmld4Mpltm1WsaMpltm1WsaLynmld4Mpltm1Wsa

class

http://purl.org/net/cito/citesAsAuthority

• Lyn<mld4>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3832561